Effects of active versus passive upper extremity neural mobilization combined with mechanical traction and joint mobilization in females with cervical radiculopathy: A randomized controlled trial

Ayub, Afsah; Osama, Muhammad; Ahmad, Shakeel

doi:10.3233/bmr-170887

Cited by 26 publications

(35 citation statements)

References 19 publications

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“…Suggests that pain relief can be related to stimulation of blood circulation which decrease muscle tone which may improve ROM, and increase pain threshold and increase superficial tissue temperature, that may stimulate Endorphin secretion, known by the natural pain killers mechanism. The results are consistent with prior studies of Traction in the treatment of CRS [1,8,11,16,17,22,35,37] where reduction of pain intensity and disability were found. Bukhari, et al (2016) [11] studied the effects of Mechanical versus Manual Traction in Manual Physical Therapy combined with segmental mobilization (SM) and exercise therapy (ET) in 36 Patients with CRS along 6 weeks by 3 days per week, results indicate that Mechanical Traction combined with SM and ET was more effectively as compared with manual traction combined with SM and ET in term of pain and disability.…”

Section: Discussionsupporting

confidence: 92%

Effect Of Cupping Massage and Modified Spinal Decompression Therapy With Exercise Therapy in Neck Radiculopathy Syndrome

Al-Jazzazi¹

2021

TURCOMAT

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Cervical radiculopathy Syndrome (CRS) is a common neuro-musculo-skeletal disorder causing pain and disability. Manual therapy interventions including cervical traction with other treatment modalities have been advocated to decrease pain and disability caused by cervical radiculopathy (CR). Al-Qudah & AL-Jazzazi (2021) conducted a new method of Spinal Decompression Therapy (SDT) in patients with Chronic Lumbar Disc Herniation (CLDH) which includes Combination of Lumbar Traction With Cervical Traction (CLTCT) as one intervention. Despite of that this new method clinically reduces pain and disability more effectively than the conventional types of Traction, CLTCT method was not previously used in CR patients nor with Cervical Disc Herniation (CDH). The clinical effectiveness of this new method with other treatment modalities in patients with CRS was not approved yet. OBJECTIVE: The purpose of the presented work is to identify the effectiveness of rehabilitative program on patients with Cervical Radiculopathy, by (15) sessions for (4) Weeks. The suggested Rehabilitative program consisted of: 1.Supine Soft Full Back, Shoulders and Neck Cupping Massage (CM) for (10) minutes, 2.CLTCT: Combined Lumbar Traction with Cervical Traction as one intervention for (20) minutes, 3.Gradual Therapeutic Exercise Package of Neck Stretching and Strengthening Exercise for approximately (15) minutes. METHODS: In this study, Five outdoor male patients had accepted to participate and were randomly chosen from Al-Karak Governmental Hospital, All subjects applied the proposed rehabilitative program. The results were analyzed using the SPSS system. RESULTS: indicates that there was statistically significant difference between the pre and post measurements in favor of the post measurements in terms of Pain, Disability. CONCLUSIONS: The present study demonstrated that the use of proposed rehabilitative program has a positive effect on patients with Cervical Radiculopathy.

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Section: Discussionsupporting

confidence: 92%

Effect Of Cupping Massage and Modified Spinal Decompression Therapy With Exercise Therapy in Neck Radiculopathy Syndrome

Al-Jazzazi¹

2021

TURCOMAT

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“…This situation is due mainly to a much more comfortable grip and control in the cervical spine than in the lumbar spine, which is a more specific technique. While Ayub et al (2019) combined traction with other treatment forms such as neural mobilization (passive vs. active), none of the treatment methods was found to be superior to the others [ 38 ]. Afzal et al (2019) also compared manual traction, manual opening techniques, and a combination of these in patients with CR, but the effects of both techniques were equally effective in functional outcome [ 37 ].…”

Section: Discussionmentioning

confidence: 99%

“…Cervical radiculopathy, thought to be mechanical, spatial dysfunction, also needs treatment, including movement, both proximally and distally. It has to be mentioned that a small number of papers used clinical tests for assessing functional outcomes [ 38 , 43 , 49 , 54 ]. This is because local pain is not the primary CR and LR problem, but distal dysfunction (e.g., muscle weakness, motor and sensory deficits due to neural malfunction), causing disability, which should always be assessed.…”

Section: Discussionmentioning

confidence: 99%

“…Nerve root will become impeded when is overstretched, or its blood supply is limited due to compression for a significantly long time, or both. Some authors applied neural mobilization techniques as a treatment for CR [ 38 ]. While Ayub et al (2019) tried to prove the different effects comparing active and passive form of this technique in a multimodal approach, Kim et al (2017) applied neural mobilization, different to the multimodal approach, but not using traction alone.…”

Section: Discussionmentioning

confidence: 99%

“…While Ayub et al (2019) tried to prove the different effects comparing active and passive form of this technique in a multimodal approach, Kim et al (2017) applied neural mobilization, different to the multimodal approach, but not using traction alone. In both cases, the effects were positive on functional outcomes [ 38 , 43 ], although the former author included only females, which may limit the generalizability of the results. So far, the question of neural mobilization techniques’ efficacy in CR remains unsolved.…”

Section: Discussionmentioning

confidence: 99%

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Manual Therapy in Cervical and Lumbar Radiculopathy: A Systematic Review of the Literature

Kuligowski

Skrzek

Cieślik

2021

IJERPH

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The aim of this study was to describe and update current knowledge of manual therapy accuracy in treating cervical and lumbar radiculopathy, to identify the limitations in current studies, and to suggest areas for future research. The study was conducted according to PRISMA guidelines for systematic reviews. A comprehensive literature review was conducted using PubMed and Web of Science databases up to April 2020. The following inclusion criteria were used: (1) presence of radiculopathy; (2) treatment defined as manual therapy (i.e., traction, manipulation, mobilization); and (3) publication defined as a Randomized Controlled Trial. The electronic literature search resulted in 473 potentially relevant articles. Finally, 27 articles were accepted: 21 on cervical (CR) and 6 in lumbar radiculopathy (LR). The mean PEDro score for CR was 6.6 (SD 1.3), and for LR 6.7 (SD 1.6). Traction-oriented techniques are the most frequently chosen treatment form for CR and are efficient in reducing pain and improving functional outcomes. In LR, each of the included publications used a different form of manual therapy, which makes it challenging to summarize knowledge in this group. Of included publications, 93% were either of moderate or low quality, which indicates that quality improvement is necessary for this type of research.

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Single‐cell analysis of Crohn's disease: Unveiling heterogeneity and evaluating ustekinumab outcomes

Li,

Sun,

Qian‐Hua

et al. 2024

The Journal of Gene Medicine

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BackgroundThe present study aimed to dissect the cellular complexity of Crohn's disease (CD) using single‐cell RNA sequencing, focusing on identifying key cell populations and their transcriptional profiles in inflamed tissue.MethodsWe applied scRNA‐sequencing to compare the cellular composition of CD patients with healthy controls, utilizing Seurat for clustering and annotation. Differential gene expression analysis and protein–protein interaction networks were constructed to identify crucial genes and pathways.ResultsOur study identified eight distinct cell types in CD, highlighting crucial fibroblast and T cell interactions. The analysis revealed key cellular communications and identified significant genes and pathways involved in the disease's pathology. The role of fibroblasts was underscored by elevated expression in diseased samples, offering insights into disease mechanisms and potential therapeutic targets, including responses to ustekinumab treatment, thus enriching our understanding of CD at a molecular level.ConclusionsOur findings highlight the complex cellular and molecular interplay in CD, suggesting new biomarkers and therapeutic targets, offering insights into disease mechanisms and treatment implications.

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Effects of active versus passive upper extremity neural mobilization combined with mechanical traction and joint mobilization in females with cervical radiculopathy: A randomized controlled trial

Cited by 26 publications

References 19 publications

Effect Of Cupping Massage and Modified Spinal Decompression Therapy With Exercise Therapy in Neck Radiculopathy Syndrome

Effect Of Cupping Massage and Modified Spinal Decompression Therapy With Exercise Therapy in Neck Radiculopathy Syndrome

Manual Therapy in Cervical and Lumbar Radiculopathy: A Systematic Review of the Literature

Single‐cell analysis of Crohn's disease: Unveiling heterogeneity and evaluating ustekinumab outcomes

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