Effects of Acute Aerobic and Anaerobic Exercise on Blood Markers of Oxidative Stress

Goldfarb, Allan H.; Wideman, L.; McKenzie, Michael J.; Consitt, Leslie A.

doi:10.1519/00124278-200505000-00007

Cited by 50 publications

(60 citation statements)

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“…These divergences between elite weightlifter and healthy sedentary subjects could be due to the training level of the subjects and the effect of training at a specific TOD (i.e., participants of the present study regularly trained between 15:30 and 17:30). In this context, Bloomer et al (7,8), Subudhi et al (40), and Ammar et al (2) indicated that being experienced resistance trained could result in a lower MDA and muscle damage levels. On the other hand, the previous studies suggest a link between the diurnal variation of the oxidative stress and the muscle damage markers (11,32).…”

Section: Discussionmentioning

confidence: 99%

Relationship between biomarkers of muscle damage and redox status in response to a weightlifting training session: effect of time-of-day

et al. 2016

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The aims of the present study were to: (1) investigate the effect of a weightlifting training session and time-of-day (TOD) upon biological parameters (i.e., oral temperature, hematological, C-reactive protein (CRP), and oxidative stress) and (2) assess their possible link with muscle damage responses. Nine weightlifters (21 ± 0.5 years) performed, in a randomized order, three Olympic-Weightlifting sessions (i.e., at 08:00, 14:00, and 18:00). Blood samples were collected at rest, 3 min and 48 h after each training session. Between pre-and post-training session, ANOVA showed significant increases in oxidative stress markers at the three TODs (p < 0.01) and significant increases for creatine kinase (CK) and lactate dehydrogenase (LDH) only at 08:00 and 18:00 (p < 0.05). At rest, the results showed a significant diurnal variation for the majority of the selected parameters except for malondialdehyde (MDA), total bilirubin, and CRP with higher values observed at 18:00 (p < 0.05). After the training session, given the higher rate of increase during the morning session, these diurnal variations persisted for temperature and WBC (p < 0.01) and were suppressed for CK, LDH, uric acid (UA), catalase, and glutathione peroxidase. The main significant correlations (p < 0.001) were observed between: (1) CK and MDA (r = 0.6) and CK and UA (r = 0.66 and r = 0.82) during the morning and evening training sessions; (2) CK and CRP only during the morning session (r = 0.5); and (3) CRP and WBC during the three training sessions (r = 0.8). In conclusion, the present findings: (1) confirm that the muscle damage responses could be induced by a high level of oxidative stress and (2) suggest to avoid scheduling training sessions in the morning given the higher muscle damage, inflammatory, and oxidative responses at this TOD.

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Section: Discussionmentioning

confidence: 99%

Relationship between biomarkers of muscle damage and redox status in response to a weightlifting training session: effect of time-of-day

et al. 2016

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“…While regular exercise is recommended to all as part of a healthy lifestyle [24,[36][37][38][39][40][41], the extent to which already-healthy young adults might benefit from regular exercise is less clear. Here, within a population of young adults of reported excellent health, regular exercise is associated with lower resting heart rate, a useful indicator of overall cardiovascular health.…”

Section: Discussionmentioning

confidence: 99%

“…However, while aerobic and anaerobic forms of exercise are commonly compared relative to biochemical [24][25][26][27][28][29] and hormonal [27,28,30,31] markers of performance, direct comparisons of their relative contributions to cardiac health are surprisingly lacking.…”

Section: Introductionmentioning

confidence: 99%

Exercise and lifestyle predictors of resting heart rate in healthy young adults

Nealen

2016

jhse

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Physical exercise is well-understood to provide significant health benefits, through physiological adaptations induced by the repeated exertion stress exercise imposes on our systems. Chief among these are cardiovascular adaptations to exercise, including adjustments of cardiac parameters such as stroke volume, heart rate, and maximal cardiac output. It is commonly assumed that aerobic forms of exercise provide greater cardiovascular benefits than do non-aerobic forms of exercise. To test this assumption, exercise habits and resting heart rate were examined in a large population of healthy young adults. 90% of subjects reported regular physical exercise, with aerobic exercise constituting 64% of all exercise hours. Subjects with a history of smoking exhibited higher resting heart rates than those with no smoking history, an effect which was due primarily to a reduction in exercise hours by smokers than due to a smoking habit itself. While both total exercise amount and aerobic exercise amount were significantly and negatively related to resting heart rate, total exercise amount was a better overall predictor of resting heart rate than was aerobic exercise amount. All forms of exercise were associated with cardiovascular health, with cardiovascular benefits accruing according to the amount of exercise performed, even in optimally healthy young adults.

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“…Τα αυξημένα επίπεδα οξειδωτικού στρες μπορεί να διαρκέσουν για αρκετές μέρες μετά το τέλος της έκκεντρης άσκησης (Close, et al, 2006;Close, et al, 2004;Close, Ashton, Cable, et al, 2005a;Nikolaidis, et al, 2007;Paschalis, et al, 2007). Aντίθετα, σε άσκηση που δεν επιφέρει μυϊκή βλάβη οι δείκτες του οξειδωτικού στρες επιστρέφουν στα φυσιολογικά επίπεδα μετά από μερικές ώρες (Aguilo, et al, 2005;Bloomer, Goldfarb, Wideman, McKenzie, & Consitt, 2005;Close, et al, 2004). Πιθανότερη αιτία για την αύξηση του οξειδωτικού στρες τις μέρες μετά από έκκεντρη άσκηση είναι η φλεγμονή που δημιουργείται στην κατεστραμμένη μυϊκή περιοχή με σκοπό τη μυϊκή επανόρθωση και αναγέννηση (Close, Ashton, McArdle, et al, 2005a;Close, Kayani, et al, 2005b;Nikolaidis, Jamurtas, et al, 2008a).…”

Section: έκκεντρη άσκηση και οξειδοαναγωγική κατάσταση του αίματοςunclassified

Η Επίδραση Της Έκκεντρης Προπόνησης Σε Δείκτες Μυϊκής Βλάβης Και Οξειδωτικού Στρες

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Anastasios A. Theodorou : The effect of eccentric training on muscle damage and redox status indices (Under the supervision of Athanasios Jamurtas, Assistand Professor)Antioxidant supplementation is quite often among athletes in an attempt to counteract the increased production of free radicals during exercise and especially after exerciseinduced muscle damage (eccentric). Recently an increasing number of studies reported negative effects of antioxidant supplementation on the training and cellular adaptations to chronic exercise. The aim of the present study was to investigate the effects of vitamin C and E supplementation on muscle performance, blood and muscle redox status, hemolysis and blood lipid profile in both trained and untrained individuals after acute and chronic exercise. After previous investigations of our group, a specific type of exercise was applied (eccentric) in order to produce long lasting and extensive changes in all biomarkers and examine more easily any effects of antioxidant supplementation. In a double-blinded fashion, participants received either a daily oral supplementation of vitamin C and vitamin E (n=14) or placebo (n=14) for eleven weeks. Following baseline tests, volunteers performed an eccentric exercise session two times per week for four weeks. Before and after the chronic eccentric exercise volunteers were subjected to one session of acute eccentric exercise, and physiological measurements were performed as well as blood samples and muscle biopsies (from 8 participants) were collected. The present results failed to support any effect of antioxidant supplementation; eccentric exercise similarly modified muscle damage and performance, blood redox status, hemolysis and lipid profile in both supplemented and non-supplemented groups. This is despite the fact that eccentric exercise induced marked changes in muscle damage and performance as well as redox status and lipid profile for several days after exercise. The complete lack of any effect on the physiological and biochemical outcome measures employed questions the validity of using orally antioxidant supplementation as redox modulators of muscle and redox status in healthy humans. Moreover, the lack of any effect of antioxidant supplementation on training and cellural adaptation to exercise observed in this study, opposed previous studies suggesting that antioxidant may block training adaptations.

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Effects of Acute Aerobic and Anaerobic Exercise on Blood Markers of Oxidative Stress

Cited by 50 publications

References 48 publications

Relationship between biomarkers of muscle damage and redox status in response to a weightlifting training session: effect of time-of-day

Relationship between biomarkers of muscle damage and redox status in response to a weightlifting training session: effect of time-of-day

Exercise and lifestyle predictors of resting heart rate in healthy young adults

Η Επίδραση Της Έκκεντρης Προπόνησης Σε Δείκτες Μυϊκής Βλάβης Και Οξειδωτικού Στρες

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