Effects of adrenergic agents on the expression of zebrafish (Danio rerio) vitellogenin Ao1

Distribution of vitellogenin in zebrafish (Danio rerio) tissues for biomarker analysis

“…VTG has been proven to be an ideal biomarker for measuring exposure to xenoestrogen in oviparous fish (Denslow et al, 1999;Heppell et al, 1995); however, recently the distribution of VTG in different tissues has been questioned. Previous studies of zebrafish have reported that VTG transcripts were detected not only in the liver, but also in extrahepatic tissues (Islinger et al, 2003;Jin et al, 2008;Tingaud-Sequeira et al, 2012;Wang et al, 2005;Yin et al, 2009), even though expression of the VTG protein has been rarely reported in extrahepatic tissues. Therefore, in this present study, the distribution of VTG (protein and mRNA transcript levels) in zebrafish was investigated.…”

Characterization, Expression Profile, and Promoter Analysis of the Rhodeus uyekii Vitellogenin Ao1 Gene

“…The third type was designated incomplete VgC, lacking phosvitin and the C -terminal peptide domain (Pv-less type) [33]. The deduced Ru-Vg lacks the vWFD and C -terminal peptide domains, similar to the Vgs of the common carp, fathead minnow, zebrafish, Chinese rare minnow, and white cloud mountain minnow [34,35,36]. According to the nomenclature of Finn and Kristoffersen [32], Vg lacking the vWFD and C -terminal peptide domains is classified as VgAo1; therefore, Ru-Vg is the VgAo1 type.…”

“…In some fish, Vg is expressed in the heart, brain, and liver of the zebrafish and in the brain and heart of the Chinese rare minnow [34,35]. In addition, similar to Ru-Vg, the Vg of the white cloud mountain minnow was expressed at a higher level in the ovary than in the liver [36]. Ru-Vg and all of the Vg genes mentioned above are AtgAo1 type [34,35,36].…”

Vitellogenin is an immunocompetent molecule for mother and offspring in fish

“…For example, expression of vg was reported in the heart and brain of the Chinese rare minnow Gobiocypris rarus [37], the ovary, gill and testis of the white cloud mountain minnow Tanichthys albonubes [38], and the gill, heart, white adipose tissue and skin of zebrafish D. rereio [39][40][41][42]. The wide extrahepatic expression of vg possibly suggests that Vg does not only function in the circulating blood, lymph and body fluid but also plays a role at the local sites after the onset of infection or injury.…”