1978
DOI: 10.1016/0026-0495(78)90257-3
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Effects of adrenergic stimulating and blocking agents on glucose-induced insulin responses in human thyrotoxicosis

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Cited by 22 publications
(10 citation statements)
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“…This is in agreement with a recent study of Wajchenberg et al (1978b) who in a small number of hyperthyroid patients observed well preserved in¬ sulin response during propranolol infusion. Since administration of propranolol caused some inhibi¬ tion of the insulin release in the same patients when rendered euthyroid, they suggested that thyroid hormones antagonize the ß-blocking effect of pro¬ pranolol on the insulin release.…”
Section: Discussionsupporting
confidence: 93%
“…This is in agreement with a recent study of Wajchenberg et al (1978b) who in a small number of hyperthyroid patients observed well preserved in¬ sulin response during propranolol infusion. Since administration of propranolol caused some inhibi¬ tion of the insulin release in the same patients when rendered euthyroid, they suggested that thyroid hormones antagonize the ß-blocking effect of pro¬ pranolol on the insulin release.…”
Section: Discussionsupporting
confidence: 93%
“…Insulin concentrations after intravenous glucose were increased {Hamada et al 1979;Wajchenberg et al 1978) or normal {Foldes et al 1981Ikejiri, Yamada and Ogura 1978) in patients whereas it was decreased in these T 4 -injected animals (Table 3). These in vivo results are in agreement with the decreased insulin secretion in vitro from perfused pancreases removed from T 4 -injected rats {Lenzen 197'8; Lenzen, Joost and Hasselblatt 1976;Hasselblatt 1976a,Lenzen andKucking 1982;Lenzen, Panten andHasselblatt 1975 Malaisse, MalaisseLagae andMcCraw 1967).…”
Section: Discussionmentioning
confidence: 90%
“…Most of the evidence in humans indicates that insulin secretion is not impaired in hyperthyroidism. Increased insulin concentrations were noted after oral glucose (Doar et al 1969;Hamada et al 1979;Kabadi and Eisenstein 1980), intravenous glucose (Baker et al 1983;Bratusch-Marrain, Gasic, Waldhausl and Hofer 1983;Hamada et al 1979;Wajchenberg et al 1978), a protein meal (Kabadi and Eisenstein 1980a) and intravenous tolbutamide (Hamada et al 1979). Normal levels have also been reported after intravenous (Andreani et al 1970) and oral (Foldes et al 1981;Ikejiri, Yamada and Ogura 1978) glucose.…”
Section: Introductionmentioning
confidence: 98%
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