Probiotics, prebiotics, synbiotics, direct-fed microbials, and herbs may improve the production efficiency in ruminants. The beneficial effect of selected specific microbes on animal health is reflected in protection against pathogens, stimulation of immunological response, increased production capacity, and mitigation of stress effects. Phytobiotic plants used in the nutrition of ruminant animals increase feed palatability. This in turn has a positive effect on feed intake and, consequently, increases production performance. Pectins, terpenes, phenols, saponins, and antibiotic-like substances contained in phytobiotics prevent irritation, diarrhea, and increase the activity of digestive enzymes. Thanks to the abundance of biologically active substances such as flavonoids, glycosides, coumarins, carotenoids, polyphenols, etc., phytobiotics exhibit immunostimulatory and antioxidant properties as well. Given such a wide range of effects on health status and production parameters in animals, an attempt was made in this review to compile the current knowledge on the possible application of these natural growth stimulants in ruminant nutrition and to demonstrate their potential benefits and/or risks for breeding these animals.