Effects of age and sex on recovery from COVID-19: Analysis of 5769 Israeli patients

Voinsky, Irena; Baristaite, Gabriele; Genevieve, David

doi:10.1016/j.jinf.2020.05.026

Cited by 135 publications

(121 citation statements)

References 8 publications

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“…Based on the patients' signs and symptoms, they were managed with isolation protocols and local guidelines. They improved within the COVID-19 recovery period based on mild to moderate pneumonia with no further deterioration during their hospital stay, and this further consolidated our diagnosis [16].…”

Section: Our Experience With the Patientssupporting

confidence: 70%

Should We Rely on Screening Tests for Further Management Alone in Polymerase Chain Reaction Negative COVID-19 Patients? A Case Series

Iqbal¹,

Ata²,

Rose³

et al. 2020

Cureus

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Section: Our Experience With the Patientssupporting

confidence: 70%

Should We Rely on Screening Tests for Further Management Alone in Polymerase Chain Reaction Negative COVID-19 Patients? A Case Series

Iqbal¹,

Ata²,

Rose³

et al. 2020

Cureus

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“…This may be one of the main reasons for having a higher rate of infection for male. However, the reasons for this sex difference remain unclear, and it was suggested that due to the defense of X chromosomes and sex hormones which play a major role in immunity for women could be a factor for women’s reduced vulnerability to viral infections (Zhu et al 2020b ; Voinsky 2020 ). Again, a higher rate of male infection could reflect a relaxed social distancing, avoiding the use of protective kits, overconfidence, and ignoring severity of the disease among the young male population than female.…”

Section: Resultsmentioning

confidence: 99%

Geospatial modelling on the spread and dynamics of 154 day outbreak of the novel coronavirus (COVID-19) pandemic in Bangladesh towards vulnerability zoning and management approaches

Rahman

Islam

2020

Model. Earth Syst. Environ.

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The novel COVID-19 is a worldwide transmitted pandemic and has received global attention. Since there is no effective medication yet, to minimize and control the transmission of the COVID-19, non-pharmaceutical interventions (NPIs) are followed globally. However, for the implementation of needful NPIs through effective management strategies and planning, space-time-based information on the nature, magnitude, pattern of transmission, hotspots, the potential risk factors, vulnerability, and risk level of the pandemic are important. Hence, this study was an attempt to in-depth assess and analyze the COVID-19 outbreak and transmission dynamics through space and time in Bangladesh using 154 day real-time epidemiological data series. District-level data were analyzed for the geospatial analysis and modelling using GIS. Getis-Ord Gi* statistics was applied for the hotspot analysis, and on the other hand, the analytical hierarchy process-based weighted sum method (AHP-WSM) was used for the modelling of vulnerability zoning of COVID-19. In Bangladesh, the status of the pandemic COVID-19 still is in exposure level. Disease transmitted at a high rate (20.37%), and doubling time of the cases were 11 days (latest week of the study period). The fatality rate was comparatively low (1.3%), and the recovery rate was about 57.50%. Geospatial analysis exhibits the disease propagates from the central parts, and Dhaka was the most exposed district followed by Chattogram, Narayanganj, Cumilla, and Bogra. A single strong clustering pattern in the central part, which spread out mainly to the southeastern part, was identified as a prime hotspot in both the cases and deaths distributions. Additionally, potential linkages between the transmission of disease and the selected factors that gear up the spreading of the disease were identified. The central, eastern, and southeastern parts were recognized as high vulnerable zone, and conversely, the western, southwestern , northwestern , and northeastern parts as medium vulnerable zone. The vulnerable zoning exercise made it possible to identify vulnerable areas with the different magnitude that require urgent intervention through proper management and action plan, and accordingly, comprehensive management strategies were anticipated. Thus, this study will be a useful guide towards understanding the space-time-based investigations and vulnerable area delineation of the COVID-19 and assist to formulate an effective management action plan to reduce and control the disease propagation and impacts. By appropriate adjustment of some factors with local relevance, COVID-19 vulnerability zoning derived here can be applied to other regions, and generally can be used for any other infectious disease. This method was applied at a regional scale, but the availability of larger scale data of the determining factors could be applied in small areas too, and accordingly, management strategies can be formulated.

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“…Evidence shows that men are at a higher predisposition to develop severe ARDS because of androgen hormones which are seen to have higher plasma levels in men as compared to women, that help drive the transcription of transmembrane protease serine 2 (TMPRSS2). 15 It is observed that comorbidities such as hypertension (27.4%) and diabetes (19.0%) increase the chances of developing ARDS and its progression from ARDS to death is furthermore increased due to older age beyond 60 years. 14 Due to the chronic hyperglycemic state seen in type 2 diabetes mellitus and chronic inflammatory state owing to excessive adipose tissue in obese patients, a delayed and depressed immune response and impaired immune memory is observed with increased risk of mortality due to COVID-19.…”

Section: Discussionmentioning

confidence: 99%

Rehabilitation of mechanically ventilated elderly patient with COVID-19 of a dedicated COVID tertiary hospital: a case report

2020

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<p class="abstract">Corona virus disease 2019 (COVID-19), a highly communicable disease caused by severe acute respiratory syndrome-corona virus 2 (SARS-CoV2) which originated in Wuhan, China has affected 213 countries worldwide and has caused an economic crisis. As of August 10, 2020, India’s recovery rate is 63%. Most of the critical cases requiring intensive care unit (ICU) management are elderly patients with co-morbidities. The case report is of an elderly, comorbid patient who was intubated and put on a mechanical ventilator. At a time when critical patients on mechanical ventilator hardly survived, this patient survived and was successfully weaned from the ventilator and extubated. The case report emphasizes physical therapy management along with medical management for an elderly SARS CoV2 survivor with co-morbidities, and his journey from the onset of symptoms to being mechanically ventilated to performing his daily activities with minimal discomfort.</p><p class="abstract"> </p>

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Effects of age and sex on recovery from COVID-19: Analysis of 5769 Israeli patients

Cited by 135 publications

References 8 publications

Should We Rely on Screening Tests for Further Management Alone in Polymerase Chain Reaction Negative COVID-19 Patients? A Case Series

Should We Rely on Screening Tests for Further Management Alone in Polymerase Chain Reaction Negative COVID-19 Patients? A Case Series

Geospatial modelling on the spread and dynamics of 154 day outbreak of the novel coronavirus (COVID-19) pandemic in Bangladesh towards vulnerability zoning and management approaches

Rehabilitation of mechanically ventilated elderly patient with COVID-19 of a dedicated COVID tertiary hospital: a case report

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