Effects of air pollution and smoking on DNA damage of human lymphocytes

Piperakis, Stylianos M.; Petrakou, Eftichia; Tsilimigaki, Smaragdi

doi:10.1002/1098-2280(2000)36:3<243::aid-em8>3.0.co;2-9

Cited by 45 publications

(14 citation statements)

References 25 publications

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“…DNA SBs in nasal mucosa cells in Florence, with a high level of ozone, were high in comparison with samples collected in Sardinia [24]. Piperakis et al [25] found no difference in levels of SBs in leukocytes between urban and rural areas in Greece.…”

Section: Comet Assaysupporting

confidence: 91%

Atmospheric pollution in Kosovo is associated with increased DNA damage in the human population

Alija¹,

Asllani²,

Bajraktari³

et al. 2016

Biomonitoring

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Abstract:In order to assess DNA damage associated with exposure to environmental pollution in two polluted sites and one control site in Kosovo, whole blood samples were collected from volunteers in two polluted areas (Kastriot/ Obiliq - lignite-based power plants and lignite mines - and Drenas/Gllogovc - Ferronikeli smelting plant) as well as from Peja, representing an unpolluted area. White blood cells were isolated, and DNA damage was analyzed by the alkaline comet assay. Significantly higher levels of DNA damage (strand breaks) were found in white blood cells from subjects living in the polluted areas compared with residents of the unpolluted city, indicating a potential threat to human health.

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Section: Comet Assaysupporting

confidence: 91%

Atmospheric pollution in Kosovo is associated with increased DNA damage in the human population

Alija¹,

Asllani²,

Bajraktari³

et al. 2016

Biomonitoring

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“…Many studies have shown that tobacco use can cause considerable damage to human DNA and could lead to cancer (3)(4). According to the World Health Organization (WHO), this number is expected to rise to more than 10 million deaths by the year 2030 (2).…”

Section: Introductionmentioning

confidence: 99%

A survey on smoking habits and attitudes among adolescents in Greece

Piperakis

Garagouni-Araiou²,

Argyracouli³

et al. 2008

International Journal of Adolescent Medicine and Health

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The objective of the present study was to investigate smoking habits among 699 secondary school students, along with their attitudes toward smoking and their perceptions on the consequences of tobacco use in their health. Our results indicate that Greek adolescents begin to smoke mainly due to curiosity and for stress reasons. Furthermore, having friends who smoke is highly associated with smoking and intention for smoking. Likewise, paternal smoking seems to reinforce students' intention for smoking. On the contrary, parental disapproval of smoking leads to anti-smoking behavior. Adolescents' attitudes toward smoking are also related to a series of similar factors such as parental educational status, parental smoking, and parental disapproval of smoking, friends who smoke, and, finally, adolescents' age, smoking behavior, and intention for smoking. The impact of tobacco use in human health seems to be understood better by older students. All these factors must be taken into account for a successful implementation of an anti-smoking intervention program.Greece has the highest percentage of smoking among European adults (9). Regarding the prevalence of smoking in Greek adolescents, research evidence indicates a high percentage of young smokers in studies conducted with 15-24 year olds (41%) and 11-13 year olds (18.6%) respectively (10-Brought to you by | University of Arizona Authenticated Download Date | 6/9/15 11:03 AM

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“…For all statistical analyses, a level of at least 0.05 was used to determine significance (Piperakis et al, 2000).…”

Section: Discussionmentioning

confidence: 99%

Effects of pulsed electric fields on DNA of human lymphocytes

et al. 2006

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The effects of pulsed electric fields of low frequency (50 Hz) on DNA of human lymphocytes were investigated. The influence of additional external factors, such as hydrogen peroxide (H2O2) and gamma-irradiation, as well as the repair efficiency in these lymphocytes, was also evaluated. The comet assay, a very sensitive and rapid method for detecting DNA damage at the single cells level was the method used. A significant amount of damage was observed after exposure to the electric fields, compared to the controls. After 2 h incubation at 37 degrees C, a proportion of damage was repaired. H2O2 and gamma-irradiation increased the damage to lymphocytes exposed to pulsed electric fields according to the dose used, while the amount of the repair was proportional to the damage.

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Effects of air pollution and smoking on DNA damage of human lymphocytes

Cited by 45 publications

References 25 publications

Atmospheric pollution in Kosovo is associated with increased DNA damage in the human population

Atmospheric pollution in Kosovo is associated with increased DNA damage in the human population

A survey on smoking habits and attitudes among adolescents in Greece

Effects of pulsed electric fields on DNA of human lymphocytes

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