Effects of Alcohol and Sleep Restriction on Simulated Driving Performance in Untreated Patients With Obstructive Sleep Apnea

Vakulin, Andrew; Baulk, Stuart D.; Catcheside, Peter; Antic, Nick A.; Heuvel, Corinna van den; Dorrian, Jillian; McEvoy, R. Doug

doi:10.7326/0003-4819-151-7-200910060-00005

Cited by 75 publications

(67 citation statements)

References 53 publications

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“…Similar to previous reports, 1,4,5,37 this study demonstrates that driving simulator performance is impaired in untreated subjects with severe OSA compared to healthy control participants. The important new findings of this study are that while driving simulator steering performance among OSA subjects improved marginally after ~3 months of CPAP treatment, driving ability remained significantly impaired compared with age-and gender-matched healthy controls.…”

Section: Discussionsupporting

confidence: 91%

“…Patients with severe OSA and healthy control subjects were a subgroup of participants recruited from an earlier study, 37 including patients who were willing to commence CPAP, and controls prepared to undertake repeat follow-up experiments and who consented to participation in the current study. The subjects included in this study were not statistically significantly different from the subjects from our previous study with respect to age, gender, BMI, sleep measures, or questionnaire results.…”

Section: Subject Selectionmentioning

confidence: 99%

“…Eighteen intervals were chosen for consistency with our previous studies. To address the question of whether or not treatment normalized steering deviation in OSA patients following 3 months treatment, and to account for known time on task effects, 37 linear mixed model analysis was used to examine fixed effects of group (OSA vs. controls), time on task (18 intervals), follow-up period (baseline vs follow-up), and all possible interactions (SPSS Inc, Version 16.0, Chicago). Subject identity was specified as a random intercept term assumed constant across conditions and using an autoregressive covariance structure (AR1) to adjust for serial correlation across the 18 time points.…”

Section: Treatment Protocolmentioning

confidence: 99%

“…Driving performance was assessed as previously described 37 using the AusEd driving simulator (Woolcock Institute for Medical Research, Sydney, Australia) which ran on a purpose-built Windows 2000 workstation (Microsoft, Redmond, Washington), 19-inch monitor (BenQ FP937s, Taipei, Taiwan), and MOMO steering wheel and pedals (Logitech, Fremont, California). The chosen simulated driving task was a 90-min country nighttime drive on a predominantly straight dual-lane road with bends occurring at 5-min intervals, each taking approximately 10 sec to negotiate.…”

Section: Main Outcome Measuresmentioning

confidence: 99%

See 3 more Smart Citations

Driving Simulator Performance Remains Impaired In Patients With Severe OSA after CPAP Treatment

Vakulin

Baulk²,

Catcheside

et al. 2011

Journal of Clinical Sleep Medicine

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Section: Discussionsupporting

confidence: 91%

Section: Subject Selectionmentioning

confidence: 99%

Section: Treatment Protocolmentioning

confidence: 99%

Section: Main Outcome Measuresmentioning

confidence: 99%

See 2 more Smart Citations

Driving Simulator Performance Remains Impaired In Patients With Severe OSA after CPAP Treatment

Vakulin

Baulk²,

Catcheside

et al. 2011

Journal of Clinical Sleep Medicine

Self Cite

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“…Outros distúrbios neurocomportamentais nesta população estão relacionados ao uso abusivo ou dependência de substâncias psicoativas, que indiretamente tem associação com os transtornos do sono 37 . Estudos mostraram alta prevalência de uso de álcool e outras drogas 12,19,38 , além da forte participação de fatores psicossociais nesta condição 8 .…”

Section: Associação Com Transtornos Neurocomportamentaisunclassified

Aspectos do sono e das funções neurocomportamentais em condutores profissionais de veículos pesados: revisão da literatura

Filho

Mussi

Sá

et al. 2011

Rev. Med. (São Paulo)

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Rev Med (São Paulo RESUMO:Caminhoneiros tipicamente têm horários de trabalho irregulares e devem freqüentemente inverter o ciclo vigília-sono, levando a privação parcial de sono cronicamente. Esta situação predispõe a elevados níveis de estresse, ao uso abusivo de drogas e psicoestimulantes, aos distúrbios alimentares, ao sedentarismo e ao desenvolvimento de doenças crônicas. Este estudo teve por objetivo revisar os distúrbios de sono e as alterações neurocomportamentais nesta população. Os autores realizaram uma discussão de 38 artigos selecionados nas bases de dados Medline, Cochrane Library, Lilacs e SciELO, usando como descritores transtornos do sono, condução de veículo, manifestações comportamentais no período de 1997 a 2010. Os autores enfatizaram neste trabalho os aspectos epidemiológicos, os fatores relacionados, os protocolos de avaliação, os instrumentos usados, as modalidades de tratamento, os distúrbios neurocomportamentais associados e as repercussões no trabalho, na saúde e na sociedade. Uma avaliação completa por profissionais capacitados na área de saúde ocupacional é fortemente recomendada na admissão, exames periódicos e na demissão destes funcionários. Faz necessário mais estudo para delinear quais os tipos de protocolos mais úteis na prática clínica, a fim de desenvolver estratégias de tratamento que contemple as necessidades destas pessoas. DESCRitORES:Transtornos do sono; Manifestações neurocomportamentais; Condução de veículo; Veículos automotores. ABStRACt:Truck drivers have typically irregular working hours and they must frequently reverse the sleep-wake cycle which leads them to a chronic partial sleep privation. This situation tpredispose them to high levels of stress, to the use of psycho stimulants and drugs to eating disorders and to sedentarism and the development of chronic diseases. This study aimed to review the sleep-wake cycle and the neurobehavioral changes in this population. The authors performed a discussion of 38 selected articles on Medline, Cochrane Library, Scielo and Lilacs, based on descriptors such as sleep disorders, vehicle driving, behavioral manifestations during the period 1997 to 2010. The authors emphasized on this study epidemiological aspects related factors, the evaluation protocols, instruments used, methods of treatment to neurobehavioral disorders and their impact on labor, health and society. A full analysis to look for qualified professionals in the field of occupational health is strongly recommended for admission, periodic examinations and for a dismissal of those employees. More study is needed to delineate which types of protocols most be useful in clinical practice, to develop treatment strategies that addresses the needs of this population.

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The impact of alcohol consumption on commercial eye blink drowsiness detection technology

Cori

Wilkinson

Jackson

et al. 2023

Human Psychopharmacology

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Introduction Driver drowsiness detection technology that assesses eye blinks is increasingly being used as a safety intervention in the transport industry. It is unclear how alcohol consumption to common legal driving limits impacts upon this technology. The aim of the study was to assess the impact of a blood alcohol content (BAC) of 0.05% and of 0.08% on drowsiness detection technology during simulated driving. Methods Participants completed a 60‐min driving simulation and sleepiness questionnaire under three conditions: 1–0.00% BAC, 2–0.05% BAC and 3–0.08% BAC. During the driving simulation task participants wore a commercial eye blink drowsiness detection technology (Optalert) with the drowsiness alarms silenced. Results Twelve participants (3 female) completed all alcohol conditions. Relative to baseline, all eye blink parameters were affected at 0.08% BAC (all p < 0.05), whereas 0.05% BAC only affected the composite eye blink drowsiness measure (the Johns Drowsiness Scale). Conclusions Alcohol consumption to 0.08% BAC impaired eye blink measures to a level that would be considered a moderate drowsiness risk. Therefore, employers should be aware that drowsiness alerts from these technologies may increase after alcohol consumption.

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Effects of Alcohol and Sleep Restriction on Simulated Driving Performance in Untreated Patients With Obstructive Sleep Apnea

Abstract: Australian National Health and Medical Research Council.

Cited by 75 publications

References 53 publications

Driving Simulator Performance Remains Impaired In Patients With Severe OSA after CPAP Treatment

Driving Simulator Performance Remains Impaired In Patients With Severe OSA after CPAP Treatment

Aspectos do sono e das funções neurocomportamentais em condutores profissionais de veículos pesados: revisão da literatura

The impact of alcohol consumption on commercial eye blink drowsiness detection technology

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