Effects of altering calcium in haemodiluted pump primes on sodium and potassium in children undergoing open-heart operations

Johnston, A. E.; Radde, Ingeborg C.; Nisbet, H. I. A.; Taylor, J.

doi:10.1007/bf03005812

Cited by 4 publications

(1 citation statement)

References 15 publications

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“…3,4 The rationale and the techniques being used for the production of profound hypothermia at The Hospital for Sick Children, Toronto, have been recently reviewed by Steward et al 5 We previously reported acid-base and electrolyte changes in several series o~ paediatrie patients undergoing open-heart surgery with normo-thermie cardiopulmonary bypass. [6][7][8] We are now reporting on a study of the acid-base and plasma electrolyte changes in infants undergoing profound hypothermia by the technique of initial surface cooling followed by further bypass cooling and rewarming. A comparison is made between the changes seen when the initial surface cooling is terminated above 30 ~ C rather than being continued to 26-27 ~ C.…”

Section: Introductionmentioning

confidence: 99%

Acid-base and electrolyte changes in infants undergoing profound hypothermia for surgical correction of congenital heart defects

Johnston

Radde

Steward

et al. 1974

Can. Anaesth. Soc. J.

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Section: Introductionmentioning

confidence: 99%

Acid-base and electrolyte changes in infants undergoing profound hypothermia for surgical correction of congenital heart defects

Johnston

Radde

Steward

et al. 1974

Can. Anaesth. Soc. J.

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Patterns of total and ionized calcium and other electrolytes in plasma during and after general surgery

Rodríguez

Jones

Adson

et al. 1976

Canad. Anaesth. Soc. J.

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CnLcitr~ plays a dominant role in many biochemical processes that are critical to body homeostasis. 1 Blood clotting and muscle contraction are two mechanisms in which ionic calcium is essential. In the myofibril, calcium ions entering the cell on depolarization, and those freed from an intracellular bound form act to cause sarcomere shortening? The other electrolytes, sodium, potassium, magnesium, and inorganic phosphate are also necessary in proper concentrations for balanced biological systems3How much of what kinds of intravenous solution to give during operation is an everyday consideration for anaesthetists. Does giving dextrose in water alter the pattern of plasma electrolytes, particularly calcium, compared to giving Ringer's lactate solution? Seeking an answer, we studied 13 patients during anaesthesia for abdominal operations who received one or other of these two intravenous solutions. PATIENTS STUDIEDThe six females and seven males averaged 55 years of age (range 39--76), and 77 kg weight (range 50-92). All were intra-abdominal operations, except for one herniorraphy. Their A.S.A. physical status categories were Class 1-8 and Class II-5.All patients were induced with thiopentone, given succinylcholine for intubation and maintained with nitrous oxide and tubocurare. In addition, halothane was given to all but two patients, who had Innovar| Nine patients, with a mean anaesthetic time of 123 minutes, received a mean volume of dextrose/water of 816 ml during operation and for one hour in the recovery room. The group who received a mean volume of 707 ml of 5 per cent dextrose/Ringer's lactate, averaged 116 minutes of anaesthesia. The intended flow rate was 250 ml per hour over the three hours. No blood was transfused. STuDY PRoTOCOLSerial samples of venous blood were drawn in heparinized syringes, without tourniquet, before induction, at mid-operation and end-operation and one hour afterwards. Samples were iced and biochemical determinations began within 15 minutes. Blood-gas analyses were done by electrodes ( Instrumentation Laboratory, Inc.) without correction for body temperature. Concentrations of several con-*From the

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A comparison of the effects of two haemodiluents on monovalent and divalent cations in children undergoing cardiopulmonary bypass and open-heart surgery

Abrahams

Johnston

Taylor

et al. 1973

Canad. Anaesth. Soc. J.

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Effects of altering calcium in haemodiluted pump primes on sodium and potassium in children undergoing open-heart operations

Cited by 4 publications

References 15 publications

Acid-base and electrolyte changes in infants undergoing profound hypothermia for surgical correction of congenital heart defects

Acid-base and electrolyte changes in infants undergoing profound hypothermia for surgical correction of congenital heart defects

Patterns of total and ionized calcium and other electrolytes in plasma during and after general surgery

A comparison of the effects of two haemodiluents on monovalent and divalent cations in children undergoing cardiopulmonary bypass and open-heart surgery

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