In this study, the ground state properties of strong-coupling polaron in RbCl quantum wells (QWs) by using double asymmetric confined potential were theoretically investigated based on effective mass approximation. Ground state binding energy (GSBE), ground state energy (GSE), vibrational frequency (VF), and mean LO phonon number (MLOPN) were obtained as functions of asymmetric confinement potential parameters in QWs by using the unitary transformation method and linear combination operator. GSBE, GSE, VF and MLOPN were found to be increasing functions of asymmetric semi-exponential confinement potential (ASECP) parameter [Formula: see text] and decreasing functions of parameter [Formula: see text]. GSE was rapidly increased with the increase of confinement strength. GSBE, GSE, VF and MLOPN increase as the increasing (decreasing) of anisotropic parabolic confinement potential strength (confinement length). In addition, the temperature effect was evaluated by using quantum statistical theory. With the increase of temperature, GSE and GSBE decreased while VF and MNLOP increased.