Effects of Anticholinergics on Death Rattle: A Systematic Review and Network Meta-Analysis

Taburee, Watcharaporn; Dhippayom, Teerapon; Nagaviroj, Kittiphon; Dilokthornsakul, Piyameth

doi:10.1089/jpm.2022.0386

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“…8 Other research demonstrates similar effectiveness between placebos and antimuscarinics including hyoscine hydrobromide, hyoscine butylbromide, atropine, and glycopyrrolate, suggesting that these secretions are likely not treatable after they're established. 7,9 Nonpharmacologic treatment includes repositioning to either a sidelying or upright position. 7 This intervention, however, may cause distress to the patient and therefore isn't normally done at the end of life.…”

Section: Treatmentmentioning

confidence: 99%

“…Research has indicated that prophylactic use of scopolamine butylbromide can significantly reduce occurrence of terminal secretions 8. Other research demonstrates similar effectiveness between placebos and antimuscarinics including hyoscine hydrobromide, hyoscine butylbromide, atropine, and glycopyrrolate, suggesting that these secretions are likely not treatable after they're established 7,9. Nonpharmacologic treatment includes repositioning to either a side-lying or upright position 7.…”

Section: Treatmentmentioning

confidence: 99%

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