ATMPH 2019
DOI: 10.36295/asro.2019.221012
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Effects of antidiabetic drug on the anticancer activity of Cisplatin

Abstract: Although its mechanism of action on cancer cells not well understood, Metformin (Met) is widely used nowadays to improve the anticancer activity of some drugs. Metformin has also been shown to decrease the growth of breast cancer cells and pancreatic cancer in hamsters and delays other types of tumors. The aim of this study was to compare the effects of Cisplatin (Cis) alone and Metformin alone on colon cancer cell line SW480. The results showed that the effect of Metformin on cell proliferation is concentrati… Show more

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“…Metformin has been found to sensitize cancer cells to Radiotherapy and Chemotherapy and potentiate the effects of Chemotherapeutic agents [50][51][52].…”
Section: Conventional Antidiabetics With Known Anticancer Effectsmentioning
confidence: 99%
“…Metformin has been found to sensitize cancer cells to Radiotherapy and Chemotherapy and potentiate the effects of Chemotherapeutic agents [50][51][52].…”
Section: Conventional Antidiabetics With Known Anticancer Effectsmentioning
confidence: 99%