Background/ObjectivesLeisure activities provide various health benefits for older adults. However, few studies have examined changes in leisure activities and health. This study aimed to determine the association among changes in leisure activities, subsequent all‐cause mortality, and functional disability.MethodsUsing a longitudinal, prospective cohort design, we analyzed data from the Japan Gerontological Evaluation Study (JAGES) in 2010 and 2013 merged with government data on death and long‐term care needs by 2020. Changes in leisure activity were defined as four‐category exposure based on a question about leisure activities: those with leisure activities in both 2010 and 2013, those who started leisure activities in 2013, those without leisure activities in both 2010 and 2013 (reference group), and those who stopped leisure activities in 2013. All‐cause mortality and functional disability were defined as onset during the 6‐year follow‐up from the 2013 survey. We applied the inverse probability of censoring and treatment‐weighted methods for analyses using Cox proportional hazards models, where missingness was addressed using multiple imputation.ResultsThe study included 38,125 participants with a mean age of 72.8 ± 5.5 years at baseline, and 46.9% were male. Among those without leisure activities between 2010 and 2013 and those who started leisure activities in 2013, mortality rates by 2020 were 28.6% and 21.1%, and functional disability rates were 24.6% and 18.1%, respectively; and in analyses with the inverse probability of censoring and treatment‐weighted methods, the hazard ratio for mortality was 0.82 (95% confidence interval (CI), 0.75–0.90) and 0.89 (95% CI, 0.79–1.01) for functional disability, respectively.ConclusionInitiation of leisure activities among the older adults was associated with a lower risk of mortality and functional disability over the subsequent 6 years compared to older adults who did not report initiating any leisure activities.