Effects of arginine and guanidinoacetic acid with or without phenylalanine on ascites susceptibility in cold-stressed broilers fed canola meal-based diet

Delfani, Negin; Daneshyar, Mohsen; Farhoomand, Parviz; Alijoo, Younes Ali; Payvastegan, Sina; Najafi, Gholamreza

doi:10.5187/jast.2022.e68

Cited by 1 publication

(1 citation statement)

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“…In the poultry industry, various factors including genetics, environment, and nutrition could affect broiler chickens’ growth performance and productivity [ 1 – 3 ]. In particular, nutrition has a vital role for maintaining the physiological barrier from diverse stress factors, such as heat, density, and diseases [ 4 ].…”

Section: Introductionmentioning

confidence: 99%

Dietary L-Methionine modulates the gut microbiota and improves the expression of tight junctions in an in vitro model of the chicken gastrointestinal tract

Kwak,

Kang,

Eor

et al. 2024

anim microbiome

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Background The poultry industry encounters a number of factors that affect growth performance and productivity; nutrition is essential for sustaining physiological status and protecting against stressors such as heat, density, and disease. The addition of vitamins, minerals, and amino acids to the diet can help restore productivity and support the body’s defense mechanisms against stress. Methionine (Met) is indispensable for poultry’s energy metabolism, physiology, performance, and feed utilization capacity. Through this study, we aimed to examine the physiological effects of methionine supplementation on poultry as well as alterations of intestinal microbiome. Methods We utilized the DL- and L- form of methionine on Caenorhabditis elegans and the FIMM (Fermentor for intestine microbiota model) in-vitro digesting system. A genomic-analysis of the transcriptome confirmed that methionine supplementation can modulate growth-related physiological metabolic pathways and immune responses in the host poultry. The C. elegans model was used to assess the general health benefits of a methionine supplement for the host. Results Regardless of the type or concentration of methionine, supplementation with methionine significantly increased the lifespan of C. elegans. Feed grade L-Methionine 95%, exhibited the highest lifespan performance in C. elegans. Methionine supplementation increased the expression of tight junction genes in the primary intestinal cells of both broiler and laying hens, which is directly related to immunity. Feed grade L-Methionine 95% performed similarly or even better than DL-Methionine or L-Methionine treatments with upper doses in terms of enhancing intestinal integrity. In vitro microbial cultures of healthy broilers and laying hens fed methionine revealed changes in intestinal microflora, including increased Clostridium, Bacteroides, and Oscillospira compositions. When laying hens were given feed grade L-Methionine 95% and 100%, pathogenic Campylobacter at the genus level was decreased, while commensal bacteria were increased. Conclusions Supplementation of feed grade L-Methionine, particularly L-Methionine 95%, was more beneficial to the host poultry than supplementing other source of methionine for maintaining intestinal integrity and healthy microbiome.

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Section: Introductionmentioning

confidence: 99%

Dietary L-Methionine modulates the gut microbiota and improves the expression of tight junctions in an in vitro model of the chicken gastrointestinal tract

Kwak,

Kang,

Eor

et al. 2024

anim microbiome

View full text Add to dashboard Cite

show abstract

Effects of arginine and guanidinoacetic acid with or without phenylalanine on ascites susceptibility in cold-stressed broilers fed canola meal-based diet

Abstract: Effects of arginine and guanidinoacetic acid supplementation with or without phenylalanine on performance and ascites susceptibility in cold-stressed broilers fed canola meal-based diet Running Title (within 10 words)Reduced adverse effects of canola meal feeding to cold-stressed broilers

Cited by 1 publication

References 86 publications

Dietary L-Methionine modulates the gut microbiota and improves the expression of tight junctions in an in vitro model of the chicken gastrointestinal tract

Dietary L-Methionine modulates the gut microbiota and improves the expression of tight junctions in an in vitro model of the chicken gastrointestinal tract

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