[Purpose] Pulmonary rehabilitation is appropriate for most individuals with chronic
obstructive pulmonary disease (COPD). Pulmonary rehabilitation consists of conditioning
and exercise therapy. Conditioning includes relaxation, breathing exercises, and manual
chest wall compression during expiration (CWC). CWC improves the symptoms in individuals
with respiratory disease who have undergone mechanical ventilation. However, evidence
supporting the effectiveness of CWC for COPD has been insufficient. This study aimed to
determine physiological responses to CWC in participants with COPD. [Participants and
Methods] Twenty-nine participants with COPD were included in the study. Manual CWC
techniques were performed in a comfortable position chosen by the participants (sitting,
forward-leaning (sitting), or semi-Fowler’s). Ventilatory parameters, occlusion airway
pressure (P0.1), and dyspnea were assessed using a visual analog scale and were
compared before and during CWC. [Results] During manual CWC, oxygen consumption, carbon
dioxide production, end-tidal carbon dioxide concentration, and dyspnea were significantly
decreased; however, P0.1 was not affected. [Conclusion] Manual CWC for COPD had
an immediate physiological effect, including a decrease in dyspnea that may have been
facilitated by a reduced workload of the respiratory muscles. Thus, manual CWC may be
effective for dyspnea by reducing oxygen consumption in the respiratory muscles.