Physical activity is beneficial for physical and mental health in the general population. Among autistic people, a range of physical and mental health conditions, particularly depression and anxiety, occur more frequently than in the general population. Physical activity interventions could help address this, but there is a lack of research in the area. The aim of this perspectives paper is to explore research into physical activity interventions for autistic adults, and identify gaps particularly in need of addressing. This perspectives paper considers six intervention studies carried out with adults, a pilot study and seven review studies of adult and child interventions. Studies found significant increases in amount of physical activity undertaken, wellbeing, interaction, emotion and regulation. There were decreases in imitative and distress behaviours. However, there were few studies, samples were small, participants all had co-occurring intellectual disability, and measures were heterogeneous with lack of assessment of changes in physical fitness levels. Qualitative exploration was extremely limited. Recommendations are that there should be increased focus on research into physical activity for autistic adults, with input from autistic people to identify enjoyable, accessible activities, particular consideration of longer-term, sustainable activities, expanding the research to include autistic people without intellectual disability, and increasing the focus on addressing mental health and anxiety through physical activity.