Effects of Bacillus cereus and coumarin on growth performance, blood biochemical parameters, and meat quality in broilers

Abstract

Background and Aim: Progressive antibiotic resistance has become the primary threat to public health. The search for alternative substances with similar effects is now a global challenge for poultry farming. The aim of this study was to investigate the action of the probiotic Bacillus cereus (BC) and coumarin (CO) on broiler productivity, biochemical indicators of blood, and muscular and liver tissues. Materials and Methods: The trial of this study included Arbor Acres cross broiler chickens that were grown up to the age of 42 days. The experiment was conducted on 200 broiler chickens divided into four experimental groups of 50 individuals each: The control group received ration without additives (main ration [MR]), the first experimental group received MR+BC, the second received MR+CO, and the third received –MR+BC+CO. A biochemical and hematological analyzer was used to estimate elemental concentrations using inductively coupled plasma mass spectrometry and inductively coupled plasma atomic emission spectrometry. Results: Inclusion of CO and CO+BC in the diet improved growth rates and reduced feed consumption (FC) per kg of live weight gain. Decreased white blood cell count, increased creatinine and triglycerides (CO), changes in aminotransferase and transpeptidase activity, and increases in chemical elements in the liver and pectoral muscles (BC+CO) were observed. The inclusion of BC+CO in the diet contributed to increases in a greater number of chemical elements in the liver (calcium [Ca], K, magnesium, Mn, Si, and Zn) and the pectoral muscles (Ca, Na, Co, Cu, Fe, Mn, Ni, and Zn). Conclusion: The inclusion of CO and CO+BC in the diet improves growth rates and reduces FC in broilers against a background of the absence of mortality during the experiment.

Effect of feeding bioactive compounds identified from plant extracts (4-hexylresorcinol, 7-hydroxycoumarin, and gamma-octalactone) on the productivity and quality of broiler meat

“…The results of our experiment are generally consistent with those of the previous research [ 32 ]. This increase in the digestibility of dietary nutrients by the administration of bioactive compounds, including those identified from coumarin, may be due to the ability of such bioactive compounds to block quorum sensing (QS) signaling systems in the gastrointestinal tract and inhibit the formation of biofilms in pathogenic bacteria [ 33 , 34 ].…”

Growth-stimulating and antioxidant effects of vanillic acid on healthy broiler chickens

“…The results of our studies showed that the separate use of vanillic acid and gamma lactone in the diet of broilers led to a significant decrease in cholesterol levels and an increase in triglycerides and UA. These data are consistent with previous experiments on Arbor Acres broilers that demonstrated increases in the blood levels of UA and triglycerides when coumarin was included in the diet [ 49 ]. Another study demonstrated a decrease in serum cholesterol levels in groups treated with antibiotics and essential oils [ 50 ].…”

Alternatives to antibiotics for organic poultry production: types, modes of action and impacts on bird's health and production

“…These cells play an essential role in the first line of defense, phagocytosing pathogens, then using oxidative burst and degranulation to destroy them. Probiotics have been shown to enhance oxidative burst and degranulation, thus protecting against pathogens ( Harmon, 1998 ; Duskaev et al, 2020 ). Heterophils isolated from probiotic-supplemented broilers displayed increased oxidative burst and degranulation ( Farnell et al, 2006 ; Stringfellow et al, 2011 ).…”