Effects of beta‐adrenoceptor antagonism on the cardiovascular and catecholamine responses to tracheal intubation

Achola, K.; Jones, Michael; Mitchell, R.W.D.; Smith, G.

doi:10.1111/j.1365-2044.1988.tb06624.x

Cited by 25 publications

(11 citation statements)

References 14 publications

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“…These stimulations trigger a wide range of sympathetic activations in the nervous system via the vagus and glossopharyngeus nerves. 13,14) Tracheal intubation is considered a stressful situation for a person undergoing general anaesthesia, which could be detrimental to patients with cardiac problems. Tachycardia and hypertension induced by TI decrease myocardial perfusion and increase oxygen consumption, both of which disrupt myocardial function.…”

Section: Discussionmentioning

confidence: 99%

Effects of Intravenous Lidocaine on QTd and HRV Changes Due to Tracheal Intubation During Sevoflurane Induction

et al. 2006

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SUMMARYThe aim of the present study was to evaluate the effects of IV lidocaine on autonomic cardiac function changes in tracheal intubation (TI) during sevoflurane anaesthesia by using more reliable parameters, namely, the analysis of QT dispersion and heart rate variability (HRV) from Holter monitoring. In this prospective, double-blind study, 44 American Society of Anaesthesiologists class I-II patients scheduled for hysterectomy were randomly and equally divided into 2 groups; a control sevoflurane group (group S, n = 22) and a lidocaine sevoflurane group (group LS, n = 22).Before the induction of anaesthesia, the electrocardiograms (ECG) of all patients were recorded for 3 minutes as baseline parameters. In both groups, the anaesthesia was induced with 7% sevoflurane in O 2 at 6L min -1 via a facemask for 2 minutes. However, before the induction of sevoflurane anaesthesia in group LS, 1 mg kg -1 of lidocaine was given intravenously (IV). For muscle relaxation during TI, vecuronium was given to all participants. Three minutes after administration of vecuronium, TI was performed and an ECG was recorded synchronously for another 3 minutes. The results from the later records were used as postintubation parameters.Baseline and postintubation data were analysed. When compared to baseline values, postintubation LF/HF and SDNN values were increased in group S (P = 0.005, P = 0.001, respectively), whereas postintubation LF and HF values were decreased in group LS (P = 0.014, P = 0.041, respectively). Under the influence of sevoflurane anaesthesia, TI resulted in sympathetic activation. However, this activation was attenuated by the administration of IV 1 mg kg -1 lidocaine 5 minutes prior to TI. (Int Heart J 2006; 47: 597-606)

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Section: Discussionmentioning

confidence: 99%

Effects of Intravenous Lidocaine on QTd and HRV Changes Due to Tracheal Intubation During Sevoflurane Induction

et al. 2006

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“…Beta-adrenoceptor blockade has proven effective in perioperative situations with increased sympathetic activity (8)(9)(10)(11)(12)(13), and attenuation of cardiovascular effects due to perioperative stimuli has been demonstrated (11)(12)(13)(14). However, the use of such drugs orally or intravenously before anaesthesia in patients not previously medicated with these drugs is still controversial (14-16).…”

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confidence: 99%

Preoperative metoprolol improves cardiovascular stability and reduces oxygen consumption after thoracotomy

Jakobsen¹,

Bille

Ahlburg³

et al. 1997

Acta Anaesthesiol Scand

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“…BIS decreased to 0 for 15 min, indicating that lidocaine and sevoflurance interact to decrease BIS. Laryngoscopy and tracheal intubation are thought to be the strongest noxious stimuli during the course of general anesthesia and are often associated with hemodynamic changes including tachycar-dia, hypertension and increases in the plasma concentration of catecholamines (Shribman et al, 1987;Achola et al, 1988). Nakatani et al(2005) investigated hemodynamic changes following induction of anesthesia with propofol during tracheal intubation with or without epidural anesthesia and found that epidural anesthesia did not produce profound hypotentension following induction of anesthesia and produced a reduction in the hemodynamic response to tracheal intubation during a target controlled infusion of propofol.…”

Section: Introductionmentioning

confidence: 99%

Comparison of 1.5% lidocaine and 0.5% ropivacaine epidural anesthesia combined with propofol general anesthesia guided by bispectral index

Xiang

2007

J. Zhejiang Univ. - Sci. B

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Abstract:Objective: To compare the effects of epidural anesthesia with 1.5% lidocaine and 0.5% ropivacaine on propofol requirements, the time to loss of consciousness (LOC), effect-site propofol concentrations, and the hemodynamic variables during induction of general anesthesia guided by bispectral index (BIS) were studied. Methods: Forty-five patients were divided into three groups to receive epidurally administered saline (Group S), 1.5% (w/w) lidocaine (Group L), or 0.5% (w/w) ropivacaine (Group R). Propofol infusion was started to produce blood concentration of 4 µg/ml. Once the BIS value reached 40~50, endotracheal intubation was facilitated by 0.1 mg/kg vecuronium. Measurements included the time to LOC, effect-site propofol concentrations, total propofol dose, mean arterial blood pressure (MABP), and heart rate (HR) at different study time points. Results: During induction of anesthesia, both Groups L and R were similar for the time to LOC, effect-site propofol concentrations, total propofol dose, MABP, HR, and BIS. The total doses of propofol administered until 1 min post-intubation were significantly less in patients of Groups R and L compared with Group S. MABP and HR were significantly lower following propofol induction compared with baseline values in the three groups, or MABP was significantly increased following intubation as compared with that prior to intubation in Group S but not in Groups R and L while HR was significantly increased following intubation in the three groups. Conclusion: Epidural anesthesia with 1.5% lidocaine and 0.5% ropivacaine has similar effects on the time to LOC, effect-site propofol concentrations, total propofol dose, and the hemodynamic variables during induction of general anesthesia.

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Effects of beta‐adrenoceptor antagonism on the cardiovascular and catecholamine responses to tracheal intubation

Abstract: The catecholamine and cardiovascular responses to laryngoscopy and tracheal intubation were studied in 20 patients who u n r k m w ! elective gynaecological surgery and ivho were allocated randoml-v to receive either practolol I0 mg or saline in travewously

Cited by 25 publications

References 14 publications

Effects of Intravenous Lidocaine on QTd and HRV Changes Due to Tracheal Intubation During Sevoflurane Induction

Effects of Intravenous Lidocaine on QTd and HRV Changes Due to Tracheal Intubation During Sevoflurane Induction

Preoperative metoprolol improves cardiovascular stability and reduces oxygen consumption after thoracotomy

Comparison of 1.5% lidocaine and 0.5% ropivacaine epidural anesthesia combined with propofol general anesthesia guided by bispectral index

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