The review encompasses the therapeutic effects of Pranayama practices on diverse health parameters. This review explores the Therapeutic Impact of Pranayama Practices on Physical and Mental Health. The authors conducted a comprehensive review of the Scopus, Research Gate, web of science, pub med and google scholar databases, looking for relevant studies focused largely on the Pranayama Practices on Physical and Mental Health. It underscores the importance of incorporating pranayama into fitness routines for a well-rounded and balanced approach to health Significant improvements in cardiovascular variables, including blood pressure, heart rate variability, and exercise tolerance. Respiratory indices, such as vital capacity and respiratory rate, displayed positive outcomes. Cognitive functions in conditions like type 2 diabetes were positively influenced by Pranayama. Mental health parameters, including stress, saw remarkable improvements. Physical fitness components, such as strength, endurance, flexibility, and body composition, demonstrated significant enhancements with the incorporation of Pranayama protocols. The review highlights the preventive and therapeutic applications of Pranayama in disorders ranging from psychosomatic conditions to chronic obstructive pulmonary disease (COPD). The evidence supports the integration of Pranayama practices into daily life for holistic health benefits. Further research is urged to unravel specific mechanisms underlying these therapeutic effects and establish optimal guidelines for incorporating Pranayama into contemporary health and wellness strategies. This review contributes to the growing body of literature on the intersection of traditional yogic practices and modern healthcare.