Effects of Caffeine on Intraocular Pressure

Abstract

In participants with open-angle glaucoma, this study identified a positive cross-sectional association between coffee consumption/higher caffeine intakes and elevated intraocular pressure.

The Effect of Caffeine on Retrobulbar Hemodynamics

“…Increased blood pressure after caffeine intake was reported in some studies, 4,7 which was not supported in some other studies. 8,28 Agaji et al 4 found an increase in systolic and diastolic blood pressure at 60 and 90 min after caffeine ingestion. Waring et al 31 evaluated the acute effects of caffeine on peripheral and central blood pressure in healthy individuals.…”

“…It has been reported in some studies that caffeine increases intraocular pressure, 4,5,18 although no change in the intraocular pressure was found in the others. [28][29][30] Chandrasekaran et al 28 evaluated the effect of coffee intake on intraocular pressure. They found a significant positive association between coffee consumption and higher mean IOP levels in participants with open angle glaucoma after multivariate adjustment.…”

The effect of caffeine on intraocular pressure: a systematic review and meta-analysis

“…In their investigation, Kang et al [39] found that for those with a self-reported family history of glaucoma, the risk of POAG with elevated IOP was associated with caffeine ingestion, while for those without family history, this relationship did not exist. In another cohort study [40], caffeine consumption was found to be associated with higher mean IOP in participants with open-angle glaucoma (OAG) than those without OAG. Possible explanations for the different responses to caffeine among different subjects may be that normal individuals with healthy drainage systems have much more ability to conduct aqueous than patients with glaucoma or OHT do.…”

Effects of caffeinated coffee consumption on intraocular pressure, ocular perfusion pressure, and ocular pulse amplitude: a randomized controlled trial

“…Additionally, coffee consumption has been associated with elevated IOP in OAG patients in a cross-sectional study. 57 Kang et al 58 found that caffeine intake may be a risk factor for incident HTG for those with a family history of glaucoma. Our study did not find that the ingestion of one cup of caffeinated coffee adversely effected IOP, OPP, or OPA among participants with a family history of glaucoma.…”