Biogas production from three different sources namely, cattle manure, cheese whey and blood, which have different characteristics, were investigated comparatively. Biogas production rates of 0.63, 0,72 and 0,64 l min PO were observed in 30 days of digestion of manure. The amount of total nitrogen (Tot-N) decreased 10% in 30 days of digestion but ammonium-nitrogen (Am-N) increased 46% at the same duration of time. Manure, during co-digestion, buffered and inoculated the cheese whey and blood, and converted them to the energy source. An average COD removal of 52% or 34% is also possible during co-digestion of cheese whey or blood with manure.