2012
DOI: 10.2298/aci1203027z
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Effects of carbonic anhydrase inhibitors on pseudophakic corneal edema

Abstract: In our study the patients who administered systemic acetazolamide had significant reduction of central corneal thickness. The folds of Descemet's membrane and endothelial dysfunction in AS OCT tomograms showed less structural changes in group I. Significant better postoperative visual acuity in these patients is probably because of the smaller corneal edema after 24 h, which improves patients' comfort.

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“…[124] However, in some clinical trials, the use of oral and topical carbonic anhydrase inhibitors was effective and safe in the prevention and post-operative control of IOP. [125] Several studies have shown that the use of these drugs did not change corneal thickness or worsen recovery from oedema after phacoemulsification. [126][127][128][129] On the other hand, there is evidence that preservatives present in hypotensive eye drops, such as benzalkonium chloride, have deleterious and toxic effects on endothelial cells.…”
Section: Iopmentioning
confidence: 99%
“…[124] However, in some clinical trials, the use of oral and topical carbonic anhydrase inhibitors was effective and safe in the prevention and post-operative control of IOP. [125] Several studies have shown that the use of these drugs did not change corneal thickness or worsen recovery from oedema after phacoemulsification. [126][127][128][129] On the other hand, there is evidence that preservatives present in hypotensive eye drops, such as benzalkonium chloride, have deleterious and toxic effects on endothelial cells.…”
Section: Iopmentioning
confidence: 99%