Effects of cardiac rehabilitation on elderly patients with Chronic heart failure: A meta-analysis and systematic review

Chen, Zhuang; Li, Ming; Cheng-hua, Yin; Fang, Youbo; Zhu, Yong‐Guan; Feng, Jing

doi:10.1371/journal.pone.0273251

Cited by 6 publications

(2 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A systematic review of randomized trials of cardiac rehabilitation in older patients with HF demonstrated that this intervention improved 6-min walk distance and decreased hospitalization, with odds ratio (95% CI) 0.32 (0.21–0.49). 19 Another systematic review confirmed that exercise-based cardiac rehabilitation decreases the risk of HF hospitalization. 20 In this systematic review, there were 33 trials that included mortality as an endpoint (666 deaths in 5441 participants), but almost all (99%) were from Europe and North America.…”

Section: Discussionmentioning

confidence: 94%

Frailty and outcomes in heart failure patients from high-, middle-, and low-income countries

Leong

Joseph

McMurray

et al. 2023

European Heart Journal

View full text Add to dashboard Cite

Background and Aims There is little information on the incremental prognostic importance of frailty beyond conventional prognostic variables in heart failure (HF) populations from different country income levels. Methods A total of 3429 adults with HF (age 61 ± 14 years, 33% women) from 27 high-, middle- and low-income countries were prospectively studied. Baseline frailty was evaluated by the Fried index, incorporating handgrip strength, gait speed, physical activity, unintended weight loss, and self-reported exhaustion. Mean left ventricular ejection fraction was 39 ± 14% and 26% had New York Heart Association Class III/IV symptoms. Participants were followed for a median (25th to 75th percentile) of 3.1 (2.0–4.3) years. Cox proportional hazard models for death and HF hospitalization adjusted for country income level; age; sex; education; HF aetiology; left ventricular ejection fraction; diabetes; tobacco and alcohol use; New York Heart Association functional class; HF medication use; blood pressure; and haemoglobin, sodium, and creatinine concentrations were performed. The incremental discriminatory value of frailty over and above the MAGGIC risk score was evaluated by the area under the receiver-operating characteristic curve. Results At baseline, 18% of participants were robust, 61% pre-frail, and 21% frail. During follow-up, 565 (16%) participants died and 471 (14%) were hospitalized for HF. Respective adjusted hazard ratios (95% confidence interval) for death among the pre-frail and frail were 1.59 (1.12–2.26) and 2.92 (1.99–4.27). Respective adjusted hazard ratios (95% confidence interval) for HF hospitalization were 1.32 (0.93–1.87) and 1.97 (1.33–2.91). Findings were consistent among different country income levels and by most subgroups. Adding frailty to the MAGGIC risk score improved the discrimination of future death and HF hospitalization. Conclusions Frailty confers substantial incremental prognostic information to prognostic variables for predicting death and HF hospitalization. The relationship between frailty and these outcomes is consistent across countries at all income levels.

show abstract

Section: Discussionmentioning

confidence: 94%

Frailty and outcomes in heart failure patients from high-, middle-, and low-income countries

Leong

Joseph

McMurray

et al. 2023

European Heart Journal

View full text Add to dashboard Cite

show abstract

“…There is, however, robust post-translational evidence for CHF. Generic cardiac and, more specifically, CHF rehabilitation are established in evidence, clinically translated by utilising multidisciplinary care to support improved outcomes [7][8][9], including in the elderly [10]. Care, with similar foundations as cardiac rehabilitation, is routinely advocated in clinical guidelines as a translational tool to enhance multidisciplinary care, following gold-standard evidence in trials and clinical translation [11].…”

Section: Introductionmentioning

confidence: 99%

Burden from Study Questionnaire on Patient Fatigue in Qualitative Congestive Heart Failure Research

Iyngkaran,

Usmani,

Bahmani

et al. 2024

JCDD

View full text Add to dashboard Cite

Mixed methods research forms the backbone of translational research methodologies. Qualitative research and subjective data lead to hypothesis generation and ideas that are then proven via quantitative methodologies and gathering objective data. In this vein, clinical trials that generate subjective data may have limitations, when they are not followed through with quantitative data, in terms of their ability to be considered gold standard evidence and inform guidelines and clinical management. However, since many research methods utilise qualitative tools, an initial factor is that such tools can create a burden on patients and researchers. In addition, the quantity of data and its storage contributes to noise and quality issues for its primary and post hoc use. This paper discusses the issue of the burden of subjective data collected and fatigue in the context of congestive heart failure (CHF) research. The CHF population has a high baseline morbidity, so no doubt the focus should be on the content; however, the lengths of the instruments are a product of their vigorous validation processes. Nonetheless, as an important source of hypothesis generation, if a choice of follow-up qualitative assessment is required for a clinical trial, shorter versions of the questionnaire should be used, without compromising the data collection requirements; otherwise, we need to invest in this area and find suitable solutions

show abstract

Influence of resistance training on muscle architecture in older adults: A systematic review and meta-analysis of randomized controlled trials

Cordeiro¹,

Linhares²,

Santos³

et al. 2023

Archives of Gerontology and Geriatrics

View full text Add to dashboard Cite

Effects of cardiac rehabilitation on elderly patients with Chronic heart failure: A meta-analysis and systematic review

Cited by 6 publications

References 17 publications

Frailty and outcomes in heart failure patients from high-, middle-, and low-income countries

Frailty and outcomes in heart failure patients from high-, middle-, and low-income countries

Burden from Study Questionnaire on Patient Fatigue in Qualitative Congestive Heart Failure Research

Influence of resistance training on muscle architecture in older adults: A systematic review and meta-analysis of randomized controlled trials

Contact Info

Product

Resources

About