Effects of CCT subunits on clinical prognosis and tumor microenvironment in thyroid cancer
Yunfeng Bai,
Xiaohui Shi
Abstract:To investigate the expression, clinical significance, mechanism of action, and tumor microenvironment (TME) of eight subunits of the chaperonin-containing TCP1 complex (CCT/TRiC) in thyroid cancer (TC). Methods:The Cancer Genome Atlas (TCGA) and high-throughput functional genome (GEO) databases were used to analyze the differential expression of each CCT subunit in TC and normal tissues, and TCGA and Gene Expression Profiling Interaction Analysis (GEPIA) were used to analyze the effects of the expression leve… Show more
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