Effects of chito-oligosaccharides supplementation on growth performance, intestinal cytokine expression, autochthonous gut bacteria and disease resistance in hybrid tilapia Oreochromis niloticus ♀ × Oreochromis aureus ♂

Supplementation of the sow diet with chitosan oligosaccharide during late gestation and lactation affects hepatic gluconeogenesis of suckling piglets

“…Zong et al (2012) reported chitosan oligosaccharides supplementation did not affect the body weight of mice (Zong et al, 2012). Recent research also found dietary supplementation with COS had no significant effect on growth performance in hybrid tilapia (Qin et al, 2014) and weaned pigs (Walsh et al, 2013). In this study, we found that maternal dietary supplementation with COS during late gestation and lactation increased the average weaning weight and average daily gain of piglet, and improved the growth rate of suckling piglets.…”

Effects of chitosan-oligosaccharides on growth performance, digestive enzyme and intestinal bacterial flora of tiger puffer (Takifugu rubripesTemminck et Schlegel, 1850)

“…Here, the COS is possibly involved in the ability to foster a favorable intestinal bacterial population, promote digestive enzyme activity, and promote growth performance. However, some researchers have observed depressed growth in rainbow trout ( Oncorhynchus mykiss ; Luo et al., ), tiger shrimp ( Penaeus monodon ; Niu et al., ), and tilapia ( Orechromis niloticus ; Qin, Hairui et al., ; Qin, Zhang et al., ). Some studies have shown that the mechanism of growth promotion by COS depends on the dosage, molecular weight, duration of feeding, environmental temperature, route of administration, and species; Dalmo and Bøgwald () and Lin, Mao, Guan, Lin, & Luo () thought the amounts used here were not sufficient to enhance the growth performance and that such supplementation does not actually affect the growth of fish.…”

“…Some studies of COS have already been conducted in mice (Cho et al., ; Kang et al., ; Okamoto et al., ), pigs (Wang, Yoo, Kim, & Kim, ; Yan & Kim, ) and broilers (Huang et al., ; Keser, Bilal, Kutay, Abas, & Eseceli, ; Zhou et al., ), and beneficial effects on growth performance, immunity, and blood profiles have also been reported. Among aquatic animals, COS have been reported to affect growth performance and immunity in Trachinotus ovatus (Lin, Mao, Guan, Lin, & Luo, ), Cyprinus carpio (Lin, Mao, Guan, Lin, Luo, Pan, ), Oncorhynchus mykiss (Luo et al., ), Orechromis niloticus (Qin, Hairui et al., ; Qin, Zhang et al., ), and Penaeus mondon (Niu et al., ).…”

Advances in characterisation and biological activities of chitosan and chitosan oligosaccharides

“…In 1984, it was first reported that chitosan, especially with 70% DD, could stimulate rats to produce nonspecific host repellence when infected with Escherichia coli and Sendai virus (Nishimura et al, 1984). These findings have led to dietary supplementation with COS being used to significantly reduce the inflammatory response in the intestine of tilapia, subsequently enhancing the health status of tilapia (Qin et al, 2014). Yang, Chou, and Li (2005) found that the antimicrobial activity of chitosan derivatives was affected by the degree of disaccharide substitution (DS), and the kind of disaccharide present in the molecule (Yang et al, 2005).…”