Mass movements processes (i.e., landslides and snow avalanches) play an important role in landscape evolution and largely affect high mountain environments worldwide and in Italy. The increase in temperatures, the irregularity of intense weather events, and several heavy snowfall events increased mass movements’ occurrence, especially in mountain regions with a high impact on settlements, infrastructures, and well-developed tourist facilities. In detail, the Prati di Tivo area, located on the northern slope of the Gran Sasso Massif (Central Italy), has been widely affected by mass movement phenomena. Following some recent damaging snow avalanches, a risk mitigation protocol has been activated to develop mitigation activities and land use policies. The main goal was to perform a multidisciplinary analysis of detailed climatic and geomorphological analysis, integrated with Geographic Information System (GIS) processing, to advance snow avalanche hazard assessment methodologies in mass movement-prone areas. Furthermore, this work could represent an operative tool for any geomorphological hazard studies in high mountainous environments, readily available to interested stakeholders. It could also provide a scientific basis for implementing sustainable territorial planning, emergency management, and loss-reduction measures.