EFFECTS OF CLONIDINE ON POLYPEPTIDE AND STEROID HORMONE LEVELS IN MAN: A review

Carlström, Kjell

doi:10.3109/00016348509157026

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1986

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“…La secrecion de GRF esta modulada por diversos esti'mulos, uno de los cuales es de tipo alfa adrenergico 15 . Utilizando un agonista alfa adrenergico como la clonidina, se podn'a explorar la reserva hipotalamica de GRF, lo que actualmente estamos efectuando en el paciente MS.…”

Section: Pacientesunclassified

El uso del factor liberador de hormona de crecimiento (GRF) como prueba de reserva hipofisiaria para hormona de crecimiento (hGH) (*)

R²,

C³

et al. 1986

Rev. chil. pediatr.

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Growth hormone releasing factor (GRF) as a test of pituitary reserve of growth hormone (hGH)Several non specific non physiological stimulatory test are used in the study of pituitary capacity to secrete hGH but none of them is completely reliable. We have used intravenous GRF (1 fjg xkg body weight) in 6 short stature but endocrinologically normal children and in 4 patients with proven hGH deficiency. The maximal plasma hGH concentration reached during the test was 47.4 ± 15.4 ng x ml in the normal children. Three of the hGH deficient patients did not respond to this provocative test; the fourth patient showed a blunted response (5.3ng x ml), suggesting a hypothalamic origin of his deficiency. GRF should be considered a good test for the diagnosis of hGH deficiency and one of the modes of therapy of this disorder in the future. (

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Section: Pacientesunclassified

El uso del factor liberador de hormona de crecimiento (GRF) como prueba de reserva hipofisiaria para hormona de crecimiento (hGH) (*)

R²,

C³

et al. 1986

Rev. chil. pediatr.

View full text Add to dashboard Cite

show abstract

EFFECTS OF CLONIDINE ON POLYPEPTIDE AND STEROID HORMONE LEVELS IN MAN: A review

Cited by 1 publication

References 15 publications

El uso del factor liberador de hormona de crecimiento (GRF) como prueba de reserva hipofisiaria para hormona de crecimiento (hGH) (*)

El uso del factor liberador de hormona de crecimiento (GRF) como prueba de reserva hipofisiaria para hormona de crecimiento (hGH) (*)

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