Effects of Combined Resistance and Endurance Training Versus Resistance Training Alone on Strength, Exercise Capacity, and Quality of Life in Patients With COPD

Zambom-Ferraresi, Fabrício; Cebollero, Pilar; Gorostiaga, Esteban M.; Moreno, Hernández; Hueto, Javier; Rodrigo, José Antonio Cascante; Rezusta, Lourdes; Val, Luis Javier López del; Antón, María M.

doi:10.1097/hcr.0000000000000132

Cited by 52 publications

(90 citation statements)

References 27 publications

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“…This finding is in line with other studies also showing improvements in quality of life after a period of exercise training [32,33] . Regular meetings of patients play a key role in quality of life; training could promote group dynamics with regard to psychosocial support [32] .…”

Section: Discussionsupporting

confidence: 82%

Benefits of High-Intensity Exercise Training to Patients with Chronic Obstructive Pulmonary Disease: A Controlled Study

et al. 2017

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Background: Various exercise training programs are used for patients with chronic obstructive pulmonary disease (COPD) of different severity. Objectives: To investigate the impact of individualized high-intensity training on exercise capacity with COPD. Methods: A total of 49 patients agreed to participate. Of these, 31 were assigned to the training group and 18 served as controls. The training group exercised twice a week for 90 min with consecutively increasing loads. At the time of enrollment (T₀), as well as after 3 (T₁) and 6 (T₂) months, a 6-min walk test (6-MWT) was performed and data on health-related quality of life, femoral muscle thickness, and various serum markers were obtained. Results: The training group improved in their 6-MWT results (T₀ = 407 ± 152 m vs. T₁ = 459 ± 127 m, p = 0.002, vs. T₂ = 483.2 ± 130.1 m, p = 0.004), in their cross-sectional area of the musculus rectus femoris (T₀ = 6.2 ± 1.2 cm² vs. T₁ = 6.9 ± 1.2 cm², p = 0.003, vs. 7.5 ± 1.6 cm², p = 0.002), and in their St. George's Respiratory Questionnaire (SGRQ) score (T₀ = 43.3 ± 18.0 vs. T₁ = 36.0 ± 18.4, p = 0.001, vs. T₂ = 34.7 ± 18. 0, p = 0.004). Serum levels of myostatin, irisin, resistin, and α-Klotho did not change significantly within the training period. Of note, the exercise group showed an inverse relationship between serum levels of resistin and those of α-Klotho after 6 months (r = -0.608, p = 0.021). Conclusions: COPD patients undergoing an individualized, structured, high-intensity training program improved their exercise capacity, gained muscle mass, and improved their quality of life.

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Section: Discussionsupporting

confidence: 82%

Benefits of High-Intensity Exercise Training to Patients with Chronic Obstructive Pulmonary Disease: A Controlled Study

et al. 2017

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“…We also found a trend for improvement in the fatigue domain with strength training. While other studies have noted improvements in most domains with both endurance training (37,42) and strength training (20,43), there are several reasons we may not have seen significant improvements. The first may be related to the fact that the interventions in the current investigation were exercise only.…”

Section: Discussioncontrasting

confidence: 63%

Comparison of Effects of Endurance and Strength Training Programs in Patients with COPD

Berry

Sheilds

Adair

2018

COPD: Journal of Chronic Obstructive Pulmonary Disease

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Comparisons between endurance and strength training in chronic obstructive pulmonary disease (COPD) patients have produced equivocal findings when examining physical function and health related quality of life (HRQL). One reason for these differences may be due to individual patient responses to the different training modalities. PURPOSE: To compare changes in physical function and HRQL in a group of COPD patients completing both an endurance and strength training program. METHODS: Eleven mildly diseased patients completed a 3 month endurance training program and, approximately 5 years later, completed a 3 month strength training program. Changes in 6 minute walk distance (6MW), time to rise from a chair 5 times (CRT) and the total score and subscores from the SF-36 and Chronic Respiratory Disease Questionnaire (CRQ) were examined. RESULTS: The forced expiratory volume as a percent of predicted remained relatively constant over the 5 years (61.1 ± 5.9 vs 60.0 ± 10.3). Endurance and strength training increased 6MW by 48.2 ± 11.2 (p = 0.008) and 39.8 ± 9.8 (p = 0.001) meters, respectively. Endurance and strength training decreased CRT by 4.8 ± 0.7 (p = 0.001) and 1.3 ± 1.2 (p = 0.056) sec, respectively. Endurance training resulted in greater improvements in HRQL as compared to strength training. CONCLUSION: These results show that walk distance improves as a result of participating in either an endurance or a strength training program. However, an endurance training program leads to greater improvements in both general and disease specific measures of HRQL.

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“…Interestingly, we observed a positive effect of the exercise program on the time needed to reach a target level of force relative to the individuals' body mass, which may have important implications in fall prevention. In addition, our exercising subjects showed substantially higher lower‐limb muscle power adaptations compared with those previously reported in COPD participants (51% vs 19%) . The fact that our subjects were specifically instructed to perform each repetition as fast and strong as possible with the load that elicited maximal power output might be behind these positive results.…”

Section: Discussionmentioning

confidence: 45%

Effects of concurrent exercise training on muscle dysfunction and systemic oxidative stress in older people with COPD

Alcázar

Losa‐Reyna

Rodríguez-López

et al. 2019

Scandinavian Med Sci Sports

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Oxidative stress is associated with disease severity and limb muscle dysfunction in COPD. Our main goal was to assess the effects of exercise training on systemic oxidative stress and limb muscle dysfunction in older people with COPD. Twenty‐nine outpatients with COPD (66‐90 years) were randomly assigned to a 12‐week exercise training (ET; high‐intensity interval training (HIIT) plus power training) or a control (CT; usual care) group. We evaluated mid‐thigh muscle cross‐sectional area (CSA; computed tomography); vastus lateralis (VL) muscle thickness, pennation angle, and fascicle length (ultrasonography); peak VO2 uptake (VO2peak) and work rate (Wpeak) (incremental cardiopulmonary exercise test); rate of force development (RFD); maximal muscle power (Pmax; force‐velocity testing); systemic oxidative stress (plasma protein carbonylation); and physical performance and quality of life. ET subjects experienced changes in mid‐thigh muscle CSA (+4%), VL muscle thickness (+11%) and pennation angle (+19%), VO2peak (+14%), Wpeak (+37%), RFD (+32% to 65%), Pmax (+38% to 51%), sit‐to‐stand time (−24%), and self‐reported health status (+20%) (all P < 0.05). No changes were noted in the CT group (P > 0.05). Protein carbonylation decreased among ET subjects (−27%; P < 0.05), but not in the CT group (P > 0.05). Changes in protein carbonylation were associated with changes in muscle size and pennation angle (r = −0.44 to −0.57), exercise capacity (r = −0.46), muscle strength (r = −0.45), and sit‐to‐stand performance (r = 0.60) (all P < 0.05). The combination of HIIT and power training improved systemic oxidative stress and limb muscle dysfunction in older people with COPD. Changes in oxidative stress were associated with exercise‐induced structural and functional adaptations.

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Effects of Combined Resistance and Endurance Training Versus Resistance Training Alone on Strength, Exercise Capacity, and Quality of Life in Patients With COPD

Cited by 52 publications

References 27 publications

Benefits of High-Intensity Exercise Training to Patients with Chronic Obstructive Pulmonary Disease: A Controlled Study

Benefits of High-Intensity Exercise Training to Patients with Chronic Obstructive Pulmonary Disease: A Controlled Study

Comparison of Effects of Endurance and Strength Training Programs in Patients with COPD

Effects of concurrent exercise training on muscle dysfunction and systemic oxidative stress in older people with COPD

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