Three complementary approaches for managing physical and psychological symptoms related to chemotherapy-induced peripheral neuropathy were evaluated against an education-only control arm. This study included 26 participants who were randomly assigned to weekly, hour-long sessions of yoga, Reiki, meditation, or an educational control experience for 6 weeks. Each participant completed pre-post measures of neurotoxicity, quality of life, psychological distress, and mindfulness. Descriptive analysis of the data indicated that all experimental group participants demonstrated improved within-group scores on quality of life and neurotoxicity outcomes following intervention; however, the improvements were not statistically significant. Neurotoxicity worsened significantly in the control group, but there were no pre-post changes with respect to quality of life, psychological distress, or mindfulness. Effect sizes were large with respect to meditation and mindfulness and with Reiki and psychological distress. Moderate effect sizes with respect to yoga and neurotoxicity and quality of life offer promise for all 3 interventions in managing chemotherapy-induced peripheral neuropathy.
KeywordsReiki, yoga, meditation, complementary and alternative medicine, neuropathy Chemotherapy-induced peripheral neuropathy is a side effect that occurs with many of the most common chemotherapeutic agents used to treat cancer. 1,2 It is the result of damage caused to the peripheral nervous system by chemotherapy and can affect sensory, motor, and autonomic neurons. 3,4 Chemotherapyinduced peripheral neuropathy can produce sensory symptoms that range from bothersome to disabling tingling, burning, numbness, loss of balance, pain, and loss of motor function that can include weakness in muscles in the upper and lower extremities. 5 Although the actual prevalence of chemotherapy-induced peripheral neuropathy is unknown, it is generally estimated at 30% to 40% in patients who have received the classes of chemotherapeutic agents used to treat breast, colon, and lung cancers, and lymphomas. 1,6-8 Typically, symptoms of chemotherapy-induced peripheral neuropathy are considered along with other pain symptoms and treated with opioids and analgesics. 9 However, these options yield limited results. With few alternatives for attenuating the symptoms of unremitting chemotherapy-induced peripheral neuropathy, people living with them have few options other than to endure them.Massage, yoga, and other complementary and alternative medical modalities have proven successful with pain and quality-of-life issues related to cancer and its treatment. [10][11][12][13] Given the limited effectiveness of allopathic intervention, the purpose of this pilot study was to determine the feasibility of using 3 complementary interventions in relieving the physical and emotional symptoms associated with chemotherapyinduced peripheral neuropathy while increasing capacity for mindfulness or self-focused attention. Of specific interest in this proposed study are 1 putative energy...