“…In particular, Petri Nets have widely been used in the medical domain for workflows modelling [15,16], access to services management [17], resource management [18], or guidelines [19], to figure out the flow of planned and executed activities to accomplish specific tasks, or to solve clinical problems. On the other hand, the deployment of technology-enhanced education has been in evolutionary development since the second half of the last century, and it is currently acknowledged as playing a pivotal role in delivering education to health professionals for the development of knowledge, skills, and behavior [20,21]. The present paper: (i) briefly reviews the theoretical background of computer-assisted education of clinical reasoning, and shows that CRM is a new concept, currently unsupported by any technology-enhanced pedagogy; (ii) describes the main features of the PN-based Health Issue Network (HIN) approach [22], whose underlying mathematical properties ensure a sound and formally correct representation of the evolutions over time of the patient's Health Issues (HIs); (iii) introduces the f-HIN model (along with its derivation, called f-HINe), as a set of user-friendly methods and tools to support undergraduate medical education for CRM, via the design and development of exercises aimed at reconstructing the network of diseases, with specific reference to multimorbidity patients; and (iv) points out in its principal functions a tailor-made software learning environment for the design, validation, and evaluation of f-HINe networks for educational purposes, called fHINscene.…”