Effects of continuous wave and fractionated diode laser on human fibroblast cancer and dermal normal cells by zinc phthalocyanine in photodynamic therapy: A comparative study

Navaeipour, Farzaneh; Afsharan, Hadi; Tajalli, H.; Mollabashi, Mahmoud; Ranjbari, Farideh; Montaseri, Azadeh; Rashidi, Mohammad-Reza

doi:10.1016/j.jphotobiol.2016.06.017

Cited by 15 publications

(7 citation statements)

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“…Consequently, 8.5 was considered as the optimized pH. These data and conclusions here are consistent with other literatures [3,25,37].…”

Section: Finding the Optimum Ph Valuesupporting

confidence: 90%

“…Analysis, detection, and quantification of biomolecules which have great impacts on people's health, are often being carried out by biosensors all around the world [1][2][3]. The use of biosensors is not just limited to health-related applications, it also plays crucial role in genetic surveillance, food quality, drug monitoring and environmental monitoring [4][5][6][7].…”

Section: Introductionmentioning

confidence: 99%

“…Electronic supplementary material The online version of this article (https://doi.org/10.1007/s00604-019-3882-y) contains supplementary material, which is available to authorized users. reliability are some of these paramount advantages [3,13]. Beside all of these, utilizing novel methods in ECL biosensors make it even more interesting.…”

Section: Introductionmentioning

confidence: 99%

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Electrochemiluminescence methods using CdS quantum dots in aptamer-based thrombin biosensors: a comparative study

et al. 2019

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The detection of thrombin by using CdS nanocrystals (CdS NCs), gold nanoparticles (AuNPs) and luminol is investigated in this work. Thrombin is detected by three methods. One is called the quenching method. It is based on the quenching effect of AuNPs on the yellow fluorescence of CdS NCs (with excitation/emission wavelengths of 355/550 nm) when placed adjacent to CdS NCs. The second method (called amplification method) is based on an amplification mechanism in which the plasmonics on the AuNPs enhance the emission of CdS NCs through distance related Förster resonance energy transfer (FRET). The third method is ratiometric and based on the emission by two luminophores, viz. CdS NCs and luminol. In this method, by increasing the concentration of thrombin, the intensity of CdS NCs decreases, while that of luminol increases. The results showed that ratiometric method was most sensitive (with an LOD of 500 fg.mL-1), followed by the amplification method (6.5 pg.mL-1) and the quenching method (92 pg.mL-1). Hence, the latter is less useful.

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“…Consequently, 8.5 was considered as the optimized pH. These data and conclusions here are consistent with other literatures [3,25,37].…”

Section: Finding the Optimum Ph Valuesupporting

confidence: 90%

Section: Introductionmentioning

confidence: 99%

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Electrochemiluminescence methods using CdS quantum dots in aptamer-based thrombin biosensors: a comparative study

et al. 2019

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“…(BISHT , WAGNER e BULMER, 2010). (KAWAUCHI et al, 2004;NAVAEIPOUR et al, 2016), enquanto em outros, a performance do laser pulsado é maior do que do laser contínuo na TFD (ESTEVEZ et al, 2010;XIAO et al, 2007). O laser pulsado pode permitir reoxigenação durante o período escuro, e teoricamente, há um aumento na formação de oxigênio singleto no sistema biológico.…”

Section: -Ensaios In Vitro De Fototoxicidadeunclassified

“…O laser pulsado pode permitir reoxigenação durante o período escuro, e teoricamente, há um aumento na formação de oxigênio singleto no sistema biológico. Existem ainda estudos que citam que a TFD utilizando luz pulsado induz a morte celular por apoptose, enquanto que a TFD utilizando luz contínua induz morte celular por necrose (KAWAUCHI et al, 2004;NAVAEIPOUR et al, 2016).…”

Section: -Ensaios In Vitro De Fototoxicidadeunclassified

Desenvolvimento de nanopartículas proteicas polimerizadas para veiculação de fotoativos aplicáveis ao tratamento de câncer do sistema nervoso central

Davanzo¹

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Ao meu orientador, Prof. Dr. Antonio Claudio Tedesco pela confiança, orientação, aprendizado e pela oportunidade de desenvolver essa pesquisa. Ao meu co-orientador, Prof. Dr. Fernando Lucas Primo que sempre me orientou, dando conselhos durante o desenvolvimento do trabalho. Aos meus pais, Maria Vanilde e Irineu, por seu amor incondicional, que sempre me deram força, apoiaram e participaram de mais essa etapa da minha vida. Obrigada por acreditarem em mim, sem vocês nada disso teria sido possível. Eu amo muito vocês. Ao meu irmão, Igor, que me acompanhou durante essa jornada, me agüentou nos momentos de estresse, sendo uma ótima companhia. Ao meu namorado e melhor amigo, Luiz Américo pela amizade, carinho, incentivo, compreensão, pelos momentos de atenção e descontração, e por me alegrar em momentos ruins. Aos amigos do Laboratório de Fotobiologia e Fotomedicina, pela amizade, e por tornarem o dia-a-dia mais alegre e descontraído. As minhas queridas amigas Mary, Gra, Jaque, e Tácila pela amizade e por sempre estarem dispostas a ajudar. A Paty que sempre me ajudou muito, e que mesmo longe considero uma grande amiga, e que com certeza fará muita falta. A Olimpia, por sua dedicação, disposição e por sempre ter um tempo para "quebrar o galho" dos alunos. À todos que acreditaram e torceram por mim. À Universidade de São Paulo e aos docentes e funcionários da FFCLRP-USP. À CAPES pela concessão da bolsa de mestrado e pelo apoio financeiro para a realização desta pesquisa. i Resumo Davanzo, N.N. Desenvolvimento de nanopartículas protéicas polimerizadas para veiculação de fotoativos aplicáveis ao tratamento de câncer do sistema nervoso central. 2016.91f. Dissertação (Mestrado).

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In VitroPhotodynamic Activities of Amphiphilic Phthalocyanine‐Amino Appendedβ‐Cyclodextrin Conjugates as Efficient Schiff Base Photosensitizer

et al. 2023

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Water‐soluble phthalocyanine has been considered as a potential photosensitizer for photodynamic therapy (PDT) applications. To achieve the best efficiency of phthalocyanine in PDT, amphiphilic zinc phthalocyanine was purposely designed and synthesized by conjugation with β‐cyclodextrin. Herein, we synthesized two novel zinc phthalocyanine derivatives connected to β‐cyclodextrin moieties through covalent Schiff base linkage (TFP‐ZnPc/AβCD). In this procedure, aldehyde substituted phthalocyanine and amino‐appended β‐cyclodextrins with different length amino side chains were used. The compounds were characterized using FT‐IR, 1H NMR, MALDI‐TOF, and UV‐vis. The newly designed photosensitizers did not self‐assemble in water and generated significant singlet oxygen via 1,3‐DPBF (1,3‐diphenylisobenzofuran) bleaching. Simultaneously, longer amino side chains increase 1O2 production efficiency. The PDT activity of the new TFP‐ZnPc/AβCD complexes was then examined on human breast cancer (MDA‐MB‐231) and fibroblast cells. In vitro results show that PDT is more effective against cancer cells than normal cells. The new TFP‐ZnPc/AβCD could be an effective PDT drug.

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Effects of continuous wave and fractionated diode laser on human fibroblast cancer and dermal normal cells by zinc phthalocyanine in photodynamic therapy: A comparative study

Cited by 15 publications

References 32 publications

Electrochemiluminescence methods using CdS quantum dots in aptamer-based thrombin biosensors: a comparative study

Electrochemiluminescence methods using CdS quantum dots in aptamer-based thrombin biosensors: a comparative study

Desenvolvimento de nanopartículas proteicas polimerizadas para veiculação de fotoativos aplicáveis ao tratamento de câncer do sistema nervoso central

In VitroPhotodynamic Activities of Amphiphilic Phthalocyanine‐Amino Appendedβ‐Cyclodextrin Conjugates as Efficient Schiff Base Photosensitizer

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