Effects of corticosterone on place conditioning to ethanol

Brooks, Simon Philip; Hennebry, G.; Croft, Adam P.; Thomas, Alyse M.; Little, H.J.

doi:10.1007/s00213-003-1745-y

Cited by 6 publications

(8 citation statements)

References 24 publications

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“…The current finding is, however, inconsistent with other data that indicate that acute CORT administration does affect ethanol-induced conditioned place preference. Brooks et al (2004) observed that acute administration of 10 mg/kg CORT to mice attenuated ethanol-induced conditioned place preference when using the conventional, alternate day, place conditioning schedule but potentiated ethanolinduced conditioned place preference when using a rapid, same day, conditioning schedule. While the conventional conditioning procedure exposes the animal to only one conditioning session per day and alternates between drug and control sessions, the rapid schedule subjects the animal to a control conditioning session immediately followed by a drug session each day.…”

Section: Effects Of Cort On Licl-induced Conditioned Place Aversionmentioning

confidence: 95%

“…This result is consistent with other research suggesting that CORT may not induce a significant conditioned place aversion. For example, administration of 10 mg/kg CORT did not produce any significant place conditioning effects (Brooks et al, 2004). Moreover, CORT administration did not produce a conditioned taste aversion when paired with a novel flavour (Kent et al, 2000(Kent et al, , 2002.…”

Section: Cort-induced Conditioned Place Aversionmentioning

confidence: 99%

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The effects of acute corticosterone on lithium chloride-induced conditioned place aversion and locomotor activity in rats

2006

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Section: Effects Of Cort On Licl-induced Conditioned Place Aversionmentioning

confidence: 95%

Section: Cort-induced Conditioned Place Aversionmentioning

confidence: 99%

The effects of acute corticosterone on lithium chloride-induced conditioned place aversion and locomotor activity in rats

2006

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“…It was reported that ethanol (0.7 and 1.5 g/kg ig) produced robust CPA, regardless of whether the rats were ethanol‐naïve or whether they had received ig ethanol (1.5 g/kg) for 15 days prior to conditioning, and regardless of whether ethanol (1 g/kg ig) was infused over 30 seconds or over 600 seconds before the conditioning sessions. Brooks et al . (2004) found ethanol‐induced CPP in mice at 2 and 2.5 g/kg ip, but not at 1.5 g/kg ip, when ethanol and vehicle conditioning were conducted on alternating days.…”

Section: Studies Using Systemic Drug Treatmentsmentioning

confidence: 99%

“…(2006). Brooks et al . (2004) found ethanol‐induced CPP in mice at 2 and 2.5 g/kg ip, but not at 1.5 g/kg ip, when ethanol and vehicle conditioning were conducted on alternating days.…”

Section: Studies Using Systemic Drug Treatmentsmentioning

confidence: 99%

REVIEW ON CPP: Measuring reward with the conditioned place preference (CPP) paradigm: update of the last decade

2007

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Conditioned place preference (CPP) continues to be one of the most popular models to study the motivational effects of drugs and non-drug treatments in experimental animals. This is obvious from a steady year-to-year increase in the number of publications reporting the use this model. Since the compilation of the preceding review in 1998, more than 1000 new studies using place conditioning have been published, and the aim of the present review is to provide an overview of these recent publications. There are a number of trends and developments that are obvious in the literature of the last decade. First, as more and more knockout and transgenic animals become available, place conditioning is increasingly used to assess the motivational effects of drugs or non-drug rewards in genetically modified animals. Second, there is a still small but growing literature on the use of place conditioning to study the motivational aspects of pain, a field of pre-clinical research that has so far received little attention, because of the lack of appropriate animal models. Third, place conditioning continues to be widely used to study tolerance and sensitization to the rewarding effects of drugs induced by pre-treatment regimens. Fourth, extinction/reinstatement procedures in place conditioning are becoming increasingly popular. This interesting approach is thought to model certain aspects of relapse to addictive behavior and has previously almost exclusively been studied in drug self-administration paradigms. It has now also become established in the place conditioning literature and provides an additional and technically easy approach to this important phenomenon. The enormous number of studies to be covered in this review prevented in-depth discussion of many methodological, pharmacological or neurobiological aspects; to a large extent, the presentation of data had to be limited to a short and condensed summary of the most relevant findings.

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“…at doses of 2.5 mg/kg and 5 mg/kg in a volume of 1 ml/kg. Doses were chosen on the basis of previous studies (Brooks et al, 2004; Graf et al, 2013). …”

Section: Methodsmentioning

confidence: 99%

Role of Hypothalamic-Pituitary-Adrenal axis and corticotropin-releasing factor stress system on cue-induced relapse to alcohol seeking

Galesi

Ayanwuyi

Garcia-Mijares

et al. 2016

European Journal of Pharmacology

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A large body of evidence has shown that the Corticotropin Releasing Factor (CRF) system, which plays a key role in stress modulation, is deeply involved in relapse to alcohol seeking induced by exposure to stressful events such as foot shock or yohimbine injections. Exposure to environmental cues is also known to be a trigger for alcohol relapse, nevertheless, the relationship between the relapse evoked by the cue-induced model and the CRF stress systems remains unclear. The purpose of this study was to evaluate, in male Wistar rats, the involvement of the CRF system and Hypothalamic-Pituitary-Adrenal (HPA) axis in relapse induced by environmental cues. Antalarmin, a selective CRF1 receptor antagonist, Metyrapone, a corticosterone (CORT) synthesis inhibitor and CORT were evaluated for their effects on the reinstatement test in a cue-induced relapse model. Antalarmin (20 mg/kg) blocked relapse to alcohol seeking induced by environmental cues. Metyrapone (50 and 100 mg/kg) also blocked relapse in Wistar rats but only at the highest dose (100 mg/kg). Corticosterone had no effect on relapse at the doses tested. The results obtained from this study suggest that the CRF stress system and the HPA axis are involved in cue-induced alcohol relapse.

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Effects of corticosterone on place conditioning to ethanol

Abstract: The effects of corticosterone on ethanol-induced place conditioning are substantially affected by the conditioning schedule used.

Cited by 6 publications

References 24 publications

The effects of acute corticosterone on lithium chloride-induced conditioned place aversion and locomotor activity in rats

The effects of acute corticosterone on lithium chloride-induced conditioned place aversion and locomotor activity in rats

REVIEW ON CPP: Measuring reward with the conditioned place preference (CPP) paradigm: update of the last decade

Role of Hypothalamic-Pituitary-Adrenal axis and corticotropin-releasing factor stress system on cue-induced relapse to alcohol seeking

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