2024
DOI: 10.1002/cplu.202400136
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Effects of Cyclic Glycopolymers Molecular Mobility on their Interactions with Lectins

Wenkang Jin,
Masanori Nagao,
Yusuke Kumon
et al.

Abstract: Cyclic polymers, which are found in the field of biopolymers, exhibit unique physical properties such as suppressed molecular mobility. Considering thermodynamics, the suppressed molecular mobility of cyclic polymers is expected to prevent unfavorable entropy loss in molecular interactions. In this study, we synthesized cyclic glycopolymers carrying galactose units and investigated the effects of their molecular mobility on the interactions with a lectin (peanut agglutinin). The synthesized cyclic glycopolymer… Show more

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