Effects of daily high-intensity exercise on myocardial perfusion in angina pectoris

Todd, Iain C.; Bradnam, Michael S.; Cooke, Michael B. D.; Ballantyne, D.

doi:10.1016/0002-9149(91)90315-c

Cited by 31 publications

(19 citation statements)

References 31 publications

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“…Previous studies performed in coronary artery disease patients explored the effects of exercise training on myocardial perfusion as evaluated by thallium scintigraphy. 10,[26][27][28][29] Shuler et al 26 evaluated the effects of a regular exercise programme (plus dietary modification) over a 1-year period in patients with chronic stable angina. Training patients (n ¼ 18, mean age 50 AE 7 years) showed a 54% reduction in reversible ischaemia, whereas no changes were observed among controls.…”

Section: Discussionmentioning

confidence: 99%

“…Training patients (n ¼ 18, mean age 50 AE 7 years) showed a 54% reduction in reversible ischaemia, whereas no changes were observed among controls. Todd et al 27 studied 40 patients (aged <60 years old) with chronic stable angina with no prior myocardial infarction. They found a 34% reduction in the extent of ischaemia in training patients (n ¼ 16) but no changes among controls.…”

Section: Discussionmentioning

confidence: 99%

“…In addition, our study patients represented a contemporary population with adoption of all up-to-date interventions and evidencebased drugs. In particular, differently from previous studies, 11,27,28,30,31 the large majority of patients were taken beta-blockers. Moreover, post-infarction patients were enrolled into a long-term exercise training programme early after the acute event, with the aim of detecting changes in myocardial perfusion early in the post-acute phase.…”

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confidence: 82%

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Effects of exercise training started within 2 weeks after acute myocardial infarction on myocardial perfusion and left ventricular function: a gated SPECT imaging study

Giallauria

Acampa

Ricci

et al. 2011

Eur J Prev Cardiolog

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 82%

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Effects of exercise training started within 2 weeks after acute myocardial infarction on myocardial perfusion and left ventricular function: a gated SPECT imaging study

Giallauria

Acampa

Ricci

et al. 2011

Eur J Prev Cardiolog

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“…Perfusion imaging was performed every heartbeat during the first pass using non-slice-selective 90 saturation-recovery preparation ultrafast steady state gradient echo sequence in 3 short-axis imaging planes, representing the basal, mid left ventricle (LV), and apical levels. Perfusion pulse sequence parameters were as follows: repetition time (per image)-200 ms, echo time-0.98 ms, inversion time-95 ms, matrix-192 Â 160, in-plane resolution-2.08 mm 2 , and slice thickness-8 mm. After the first FPCE MR examination, approximately 5 min were spent on the preparation procedures which included measuring BP, setting up the infusion set and coaching the patients.…”

Section: Mr Protocolmentioning

confidence: 99%

“…Several studies have also demonstrated that exercise training can improve myocardial perfusion in patients with coronary artery disease (2)(3)(4)(5). Recently, cardiovascular MR (CMR) has been used both to assess the myocardial perfusion in patients with myocardial infarction (MI) (6) and to evaluate the exercise effects using a semi-quantitative approach (7).…”

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confidence: 99%

Exercise training increases myocardial perfusion in residual viable myocardium within infarct zone

Lee

et al. 2011

Magnetic Resonance Imaging

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Purpose: To study the effect of exercise training on the myocardial perfusion in the postinfarct myocardium.Materials and Methods: Twenty-nine patients with stable chronic myocardial infarction were randomly assigned to either a training group (N ¼ 17) or a control group (N ¼ 12). The training group received a 3-month exercise program. Cardiovascular MR was first performed before the training to establish a baseline, and subsequently performed once again upon conclusion of the program. Late gadolinium enhancement was used both to define the infarct and remote zones and to quantify the ratio of the residual viable myocardium (VMR) within the infarct zone. The myocardium was divided into subendocardial and subepicardial layers with equal thickness. The interval change of myocardial perfusion reserve (MPR) was computed for each zone and layer. The association between the exercise-induced perfusion change and VMR was analyzed for layers of the infarct zone.Results: In the training group, the remote zone showed significantly increased MPR. The infarct zone showed no perfusion change in the subendocardial layer, but it demonstrated significantly increased MPR in the subepicardial layer. In the infarct zone, the change in MPR was associated with VMR. Conclusion:In chronic myocardial infarction, the exercise-induced perfusion change in the infarct zone is proportional to the amount of residual viable myocardium.

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Exercise-based cardiac rehabilitation for adults with stable angina

Long

Anderson

Dewhirst

et al. 2018

Cochrane Database of Systematic Reviews

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Due to the small number of trials and their small size, potential risk of bias and concerns about imprecision and lack of applicability, we are uncertain of the effects of exercise-based CR compared to control on mortality, morbidity, cardiovascular hospital admissions, adverse events, return to work and health-related quality of life in people with stable angina. Low-quality evidence indicates that exercise-based CR may result in a small increase in exercise capacity compared to usual care. High-quality, well-reported randomised trials are needed to assess the benefits and harms of exercise-based CR for adults with stable angina. Such trials need to collect patient-relevant outcomes, including clinical events and health-related quality of life. They should also assess cost-effectiveness, and recruit participants that are reflective of the real-world population of people with angina.

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Effects of daily high-intensity exercise on myocardial perfusion in angina pectoris

Cited by 31 publications

References 31 publications

Effects of exercise training started within 2 weeks after acute myocardial infarction on myocardial perfusion and left ventricular function: a gated SPECT imaging study

Effects of exercise training started within 2 weeks after acute myocardial infarction on myocardial perfusion and left ventricular function: a gated SPECT imaging study

Exercise training increases myocardial perfusion in residual viable myocardium within infarct zone

Exercise-based cardiac rehabilitation for adults with stable angina

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