Effects of demographic and physical factors on nerve conduction study values of healthy subjects in a multi-ethnic Asian population

Fong, Sue-Yng; Goh, Kim‐Leng; Shahrizaila, Nortina; Wong, Kum-Thong; Tan, Chong-Tin

doi:10.1002/mus.25029

Cited by 34 publications

(39 citation statements)

References 31 publications

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“…Children aged 4 years and above were considered to have attained adult NCS reference ranges . Hence, for this group, abnormal values were defined as more than 2 standard deviations above/below our laboratory's normal mean values . Electrophysiological evidence of neuropathy (electrophysiological neuropathy) was defined as the presence of abnormal NCS parameters (including distal motor latencies, motor and sensory action potential amplitudes and/or motor and sensory nerve conduction velocities) in two or more nerves.…”

Section: Methodsmentioning

confidence: 99%

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Vincristine‐induced peripheral neuropathy in survivors of childhood acute lymphoblastic leukaemia

Tay

Lee

Ong

et al. 2017

Pediatric Blood & Cancer

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Section: Methodsmentioning

confidence: 99%

“…20 Hence, for this group, abnormal values were defined as more than 2 standard deviations above/below our laboratory's normal mean values. 21…”

Section: Assessmentmentioning

confidence: 99%

Vincristine‐induced peripheral neuropathy in survivors of childhood acute lymphoblastic leukaemia

Tay

Lee

Ong

et al. 2017

Pediatric Blood & Cancer

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“…3,11,21 Most of our values were similar to four other similar published studies. 2,3,5,8,13,21,22,23 However, there were some differences, which could be attributed to different NCS techniques, machine settings, and demographic characteristics. A notable dissimilarity was in the CMAP and the SNAP amplitudes because some studies used peak-to-peak measurement and others used baseline-to-negative peak measurements.…”

Section: Discussionmentioning

confidence: 99%

Untitled

2019

JNSK

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Background: nerve conduction study (NCS) is a neurophysiologic medical diagnostic test used commonly to evaluate the function of the peripheral nerves. It is an extension to the clinical examination and extremely useful to diagnose and document a peripheral nerve disorder, localize the lesion, and to establish underlying pathophysiology. Objective: The aim of this study is to evaluate the influence of gender on nerve conduction study values and to generate reference nerve conduction studies (NCS) data for the commonly tested nerves among healthy adults in Oman. Subjects and methods: This study was conducted in the Neurology Department at the Royal Hospital, a tertiary care hospital in Muscat-Oman, for a period of four years (from March 2015 until May 2019) which included a total of 143 (80 females and 63 males) healthy Omani subjects. Sensory and motor nerve conduction studies were performed to the Median, Ulnar, Peroneal and Tibial nerves to establish the normative data. Statistical analysis was performed using Minitab comparing the mean values of all NCS parameters for both genders. Results: Gender comparison concluded that Omani males have longer distal motor latencies for all of the tested nerves and slower motor conduction velocities for the lower limbs' nerves (p <0.005) than the females. While sensory latencies were significantly delayed in males as compared to Omani females for the upper limbs' nerves and the ensory nerve potential amplitudes in the upper limbs were greater in females (p<0.0001) than males. A normative data for distal latencies, conduction velocities and responses amplitudes for motor and sensory nerves were sat up for the first time for normal adult Omani population. Conclusion: Gender has a significant influence on distal latencies and conduction velocities of some peripheral nerves in healthy Omani adult subjects, suggesting that different cutoff values for the two genders may be needed for interpreting such studies. These differences could be related to anatomical (height and limbs' length gender differences) and/or physiological factors. Our normative data for nerve conduction study values are comparable to other published studies in the literature.

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“…Both the sural nerves are to be abnormal to conclude the case to be a Diabetic poly neuropathy case. Fong SY, Goh KJ, Shahrizaila N, et al 14 The clinical and economic burden of diabetic poly neuropathy is because of its role in foot ulceration and lower limb amputation, susceptibility to falls and fractures and reduced quality of life. Glycaemic control slows the progression of Diabetic poly neuropathy.…”

Section: Discussionmentioning

confidence: 99%

Nerve Conduction Velocity Studies in Patients With Diabetes Mellitus (Type 2)

Munagavalasa¹,

Nalli²

2019

jebmh

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BACKGROUND Nerve conduction velocity study is a tool to assess the functional status of the sensory as well as motor nerves under physiological and pathological background. This study is done in association with the department of neurology where most of the cases were due to neuropathy caused by diabetes mellitus. METHODS The present study is a prospective study. It includes 40 patients suffering from type 2 diabetes mellitus of less than 2 years duration. These patients include both men and women in the age group of 45 to 55 years. Nerve conduction velocity study test is performed on them with the help of electromyogram. RESULTS According to this study, the nerve conduction velocity tests show abnormal nerve conduction in the motor nerves than in the sensory nerves. It also shows that neuropathy with decreased nerve conduction velocity is observed in the lower limbs frequently. CONCLUSIONS Nerve conduction velocity test is a simple and non-invasive test to diagnose neuropathy. It is useful in the prevention, detection and management of neuropathies.

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Effects of demographic and physical factors on nerve conduction study values of healthy subjects in a multi-ethnic Asian population

Abstract: NCS parameters in multi-ethnic Malaysians were influenced independently by various demographic and physical factors, including ethnicity. Muscle Nerve 54: 244-248, 2016.

Cited by 34 publications

References 31 publications

Vincristine‐induced peripheral neuropathy in survivors of childhood acute lymphoblastic leukaemia

Vincristine‐induced peripheral neuropathy in survivors of childhood acute lymphoblastic leukaemia

Untitled

Nerve Conduction Velocity Studies in Patients With Diabetes Mellitus (Type 2)

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