Effects of deproteinization methods on primary structure and antioxidant activity of Ganoderma lucidum polysaccharides

Zeng, Xiaotong; Li, Panyu; Chen, Xi; Kang, Yan; Xie, Yi; Li, Xiang; Xie, Tian; Zhang, Yongkui

doi:10.1016/j.ijbiomac.2018.12.222

Cited by 90 publications

(30 citation statements)

References 63 publications

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“…The deproteinization involves the disruption of chemical bonds between proteins and chitin, requiring chemicals to depolymerize the biopolymer [ 48 ], whose removal of the associated proteins is an essential step in the polysaccharide purification process [ 49 , 50 ].…”

Section: Chitin Isolation From Natural Resourcesmentioning

confidence: 99%

Seafood Waste as Attractive Source of Chitin and Chitosan Production and Their Applications

Santos

Marques

Maia

et al. 2020

IJMS

282

123

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Chitosan is a cationic polymer obtained by deacetylation of chitin, found abundantly in crustacean, insect, arthropod exoskeletons, and molluscs. The process of obtaining chitin by the chemical extraction method comprises the steps of deproteinization, demineralization, and discoloration. To obtain chitosan, the deacetylation of chitin is necessary. These polymers can also be extracted through the biological extraction method involving the use of microorganisms. Chitosan has biodegradable and biocompatible properties, being applied in the pharmaceutical, cosmetic, food, biomedical, chemical, and textile industries. Chitosan and its derivatives may be used in the form of gels, beads, membranes, films, and sponges, depending on their application. Polymer blending can also be performed to improve the mechanical properties of the bioproduct. This review aims to provide the latest information on existing methods for chitin and chitosan recovery from marine waste as well as their applications.

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Section: Chitin Isolation From Natural Resourcesmentioning

confidence: 99%

Seafood Waste as Attractive Source of Chitin and Chitosan Production and Their Applications

Santos

Marques

Maia

et al. 2020

IJMS

282

123

View full text Add to dashboard Cite

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“…Though peptide from extracts showed antioxidant and anticancer activities, the extracts containing impurities like proteins may greatly limit their application in the fields of medicine and food, such as serious allergic reactions [ 28 – 30 ]. But proteins cannot be completely removed due to the intensive binding of some proteins to polysaccharides and the existence of glucoprotein or proteoglycan [ 31 ].…”

Section: Discussionmentioning

confidence: 99%

Optimization of Liquid Culture Condition of a Novel Fungus Hygrophoropsis sp. and Antioxidant Activity of Extracts

Huang

Sun

et al. 2020

Biochemistry Research International

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To evaluate pharmacological activities of a novel fungus Hygrophoropsis sp., the influence of aeration rate on the production of mycelial biomass, exopolysaccharides (EPS), and intrapolysaccharides (IPS) in the fungus Hygrophoropsis sp. was investigated. And the water extracts of cultured Hygrophoropsis sp. mycelia and the fermentation broth were analyzed for their antioxidation activity by using four different assay methods such as hydroxyl radical scavenging, superoxide radical scavenging, hydrogen peroxide scavenging, and reducing power. The Hygrophoropsis sp. was cultivated under various aeration rates in a 7 l bioreactor. The highest mycelial biomass (3.98 mg/mL) and IPS production (19.63 mg/g) were obtained at aeration rate 4.5 v.v.m. The results showed that Hygrophoropsis sp., in general, possesses a strong antioxidation activity in all assays tested. The deproteinized extracts had stronger antioxidation activity as compared to the un-deproteinized extracts by using superoxide radical scavenging, hydrogen peroxide scavenging, and reducing power. Besides, the un-deproteinized extracts had stronger antioxidation activity as compared to the deproteinized extracts by using hydroxyl radical scavenging. Thus, the polysaccharide extractions from the Hygrophoropsis sp. studied have antioxidant activities in vitro, which may be a good source of natural antioxidants or further investigation as potential natural antioxidants.

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“…The best known polysaccharides from G. lucidum , the pure glucose polymer (GLP-1) and the polymer built of β-D-glucose and α-D-galactose (GLP-2) show particular antioxidant activities [ 9 ]. These properties result from the presence of various functional groups that are electron and hydrogen donors [ 8 , 10 ]. Modifications to polysaccharides are now commonly performed to improve the structural composition, bonding, molecular weight and ionic nature of such a polymer.…”

Section: Introductionmentioning

confidence: 99%

Health-Promoting of Polysaccharides Extracted from Ganoderma lucidum

2021

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Medicinal mushrooms are rich sources of pharmacologically active compounds. One of the mushrooms commonly used in traditional Chinese medicine is Ganoderma lucidum (Leyss. Ex Fr.) Karst. In Asian countries it is treated as a nutraceutical, whose regular consumption provides vitality and improves health. Ganoderma lucidum is an important source of biologically active compounds. The pharmacologically active fraction of polysaccharides has antioxidant, immunomodulatory, antineurodegenerative and antidiabetic activities. In this review, we summarize the activity of Ganoderma lucidum polysaccharides (GLP).

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Effects of deproteinization methods on primary structure and antioxidant activity of Ganoderma lucidum polysaccharides

Cited by 90 publications

References 63 publications

Seafood Waste as Attractive Source of Chitin and Chitosan Production and Their Applications

Seafood Waste as Attractive Source of Chitin and Chitosan Production and Their Applications

Optimization of Liquid Culture Condition of a Novel Fungus Hygrophoropsis sp. and Antioxidant Activity of Extracts

Health-Promoting of Polysaccharides Extracted from Ganoderma lucidum

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