“…Lidocaine has several properties that can explain salutary effects on spinal cord injury‐related ileus. A direct excitatory effect on intestinal smooth muscle, 15 blockade of the afferent and/or efferent link of the sympathetic inhibitory spinal reflexes 16 and inhibition of neuronal and reflex responses to colonic distension 13,17 are probably involved. An anti‐inflammatory effect, 3,18 especially on inflammation due to peritoneal distension 13,19 and post‐traumatic or post‐surgical stress, 20–22 could also be hypothesized.…”