Effects of Destruction of Hypothalamus by Tumor

Collins, V. Peter

doi:10.1001/archneurpsyc.1942.02290110094004

Cited by 12 publications

(2 citation statements)

References 19 publications

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“…Surgical damage to the right temporal lobe is also visible. (Collins, 1942;Haugh and Markesberry, 1983;Killeffer and Stern, 1970;Reeves and Plum, 1969). In the current patient these features were the most conspicuous aspects of the clinical presentation.…”

Section: Discussionmentioning

confidence: 50%

Altered Behavior Associated with Damage to the Ventromedial Hypothalamus: A Distinctive Syndrome

Flynn

Cummings

Tomiyasu

1988

Behavioural Neurology

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An adult manifested a tetrad of neurobehavioral findings consisting of episodic rage, emotional lability, hyperphagia with obesity, and memory impairment with intellectual decline following surgical removal of a craniopharyngioma. Post-mortem investigation of the topography of the lesion as well as review of previously reported cases suggest that this tetrad represents a specific neurobehavioral syndrome referable to damage to the ventromedial hypothalamus.

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Section: Discussionmentioning

confidence: 50%

Altered Behavior Associated with Damage to the Ventromedial Hypothalamus: A Distinctive Syndrome

Flynn

Cummings

Tomiyasu

1988

Behavioural Neurology

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“…The following abnormalities are ascribed to the destruction of this region by a tumour: diabetes insipidus; suppression of functions of the anterior lobe of the pituitary, the thyroid, the ovaries, and the adrenal glands ; dis turbance of fat metabolism, of sleep, of thermal regulation, and of personality (6).…”

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confidence: 99%

Visceral Functions of the Nervous System

McSwiney¹

1944

Annu. Rev. Physiol.

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It is interesting to recall that some forty years ago Sherrington (1) included a description of spinal visceral reflexes in a chapter on "The Spinal Cord" which he contributed to Schafer's Text Book of Physiology. In the course of the article he drew attention to the fact that after destruction of the higher nerve centres, e.g. brain, the competence remaining to the spinal centres is found great�st for visceral reactions. From this point of view the visceral reflexes present the most per fect reactions of the spinal animal. The bulbo-spinal animal, receiving as it does the afferent impulses of the vagus as well as of the thoracic and sacral nerves, may indeed be considered as regards visceral function a fairly perfect animal. The purely spinal animal does, however, exhibit some amount of damage to the nervous regulation of its viscera; this is chiefly of the nature of "shock" and temporary.Magoun (2) rightly points out that "the full role of the auto nomic syst�m in the integration of bodily processes is only exerted through the action of essential supranuclear centres in the medulla, hypothalamus, and cerebral cortex." It should be emphasized, however, that the vis � era, though dependent on the nervous sys tem for the integration of reactions and necessary adjustments, are capable of independent function after section of the extrinsic nerves.It is intended to include in this chapter studies on the represen tation of the sympathetic and parasympathetic systems in the cerebral cortex, hypothalamus, medulla, and the s pinal cord, to gether with investigations on the autonomic nerves in their more general aspects. Papers concerned with the problem of visceral sensation, including referred pain, will also be discussed, and refer ence will be made to the viscerosomatic and somaticovisceral re flexes which seem logically to belong to this section. CENTRES Cerebral cortex.-Few papers describing the influence of the cortex on the discharge of impulses by way of the autonomic nerv ous system have appeared during the year.365 Annu. Rev. Physiol. 1944.6:365-390. Downloaded from www.annualreviews.org Access provided by University of Bath on 02/04/15. For personal use only. Quick links to online content Further ANNUAL REVIEWS

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Hypothyroidism and Alveolar Hypoventilation

Weg¹

1965

Arch Intern Med

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Effects of Destruction of Hypothalamus by Tumor

Cited by 12 publications

References 19 publications

Altered Behavior Associated with Damage to the Ventromedial Hypothalamus: A Distinctive Syndrome

Altered Behavior Associated with Damage to the Ventromedial Hypothalamus: A Distinctive Syndrome

Visceral Functions of the Nervous System

Hypothyroidism and Alveolar Hypoventilation

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