In this study, reaction cross-section calculations of some proton-induced reactions on natPd have been investigated under the effects of level density models. All calculations involving level density models have been done employing the TALYS code’s 1.95 version. TALYS is an open-source software. It gives foresight to the researchers about many parameters of a desired nuclear reaction, one of which is known as cross-section, when it is not possible to perform it due to specific reasons. The TALYS 1.95 code consists of six different level density models, which have all been included in this study. All obtained cross-section results gathered from the utilization of level density models have been compared with available experimental data. The mentioned available experimental data used in this study have been obtained from the International Experimental Nuclear Reaction Data Library (EXFOR) database. A graphical representation of generated calculation results, and available experimental data have been displayed for these comparisons. These graphical representations are also used to point out the most consistent level density model with respect to the experimental data for each reaction investigated in this study. The use of level density models was found to affect the results of cross-sectional calculations.