Effects of Diet on Fish Oil Toxicity in the Rat

Ershoff, Benjamin H.

doi:10.1093/jn/71.1.45

Cited by 10 publications

(2 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Contrary to the report by Ershoff (1960), the addition of cod-liver oil caused neither a retardation in weight increase nor diarrhoea over the 29 days of the experiment. The gain in weight of the males receiving the basal low-fat diet was similar to that reported by Ershoff, 27, 58, 99 and 129 g for the 8th, Igth, 22nd and 29th days of feeding, compared with 27, 64, 93 and 124 g for the 7th, 14th, 21st and 28th days of feeding.…”

Section: Discussioncontrasting

confidence: 99%

Growth of rats given cod-liver oil

Ward¹,

Amos²

1962

Br J Nutr

View full text Add to dashboard Cite

Section: Discussioncontrasting

confidence: 99%

Growth of rats given cod-liver oil

Ward¹,

Amos²

1962

Br J Nutr

View full text Add to dashboard Cite

“…At that time, the effect was surprising as the sesame oil meal contained 11.5 mg tocopherols/kg diet and the soybean oil meal had 27.5 mg/kg. Sesamol was also mentioned to counteract fish oil toxicity to chicks in a similar manner to the antioxidants ct-T and x,x'diphenyl-p-phenyl-enediamine (17).…”

Section: Discussionmentioning

confidence: 99%

Sesamin (a compound from sesame oil) increases tocopherol levels in rats fedad libitum

Kamal‐Eldin

Pettersson

Appelqvist

1995

Lipids

View full text Add to dashboard Cite

Six groups of rats were fed diets low, but adequate, in alpha-tocopherol but high in gamma-tocopherol. The six diets differed only in their contents (0, 0.25, 0.5, 1.0, 2.0, and 4.0 g/kg, respectively) of sesamin, a lignan from sesame oil. After four weeks of ad libitum feeding, the rats were sacrificed and the concentrations of alpha- and gamma-tocopherols were measured in the plasma, livers, and lungs. Sesamin-feeding increased gamma-tocopherol and gamma-/alpha-tocopherol ratios in the plasma (P < 0.05), liver (P < 0.001), and lungs (P < 0.001). The increase was non-significant for alpha-tocopherol. Thus, sesamin appears to spare gamma-tocopherol in rat plasma and tissues, and this effect persists in the presence of alpha-tocopherol, a known competitor to gamma-tocopherol. This suggests that the bioavailability of gamma-tocopherol is enhanced in phenol-containing diets as compared with purified diets.

show abstract

A comparison of the effects of the polyunsaturated fatty acids of cuttlefish liver oil and cottonseed oil on cholesterol metabolism

Kaneda

Alfin-Slater

1963

J Americ Oil Chem Soc

View full text Add to dashboard Cite

Rats red ad lib. for 12 weeks either a fat‐free diet, a diet containing 15% cottonseed oil, or a diet containing 15% cuttlefish liver oil, with or without exogenous (1%) cholesterol, were studied to evaluate and compare the effect of polyunsaturated fatty acids of cuttlefish liver oil and cottonseed oil on cholesterol metabolism. The results indicate that the longer chain polyunsaturated fatty acids contained in the fish oil cannot substitute for the essential fatty acid, linoleic, either as far as effect on various aspects of cholesterol metabolism are concerned or in the ability to form arachidonic acid. The observed interference of cuttlefish liver oil with the absorption of exogenous cholesterol may be caused by the presence in this oil of the highly unsaturated long chain fatty acids.

show abstract

Effects of Diet on Fish Oil Toxicity in the Rat

Cited by 10 publications

References 17 publications

Growth of rats given cod-liver oil

Growth of rats given cod-liver oil

Sesamin (a compound from sesame oil) increases tocopherol levels in rats fedad libitum

A comparison of the effects of the polyunsaturated fatty acids of cuttlefish liver oil and cottonseed oil on cholesterol metabolism

Contact Info

Product

Resources

About