Effects of dietary carboxymethyl pachyman on oxidative stress and inflammation in weaned piglets challenged with diquat

The Impacts of Dietary Fermented Mao-tai Lees on Growth Performance, Plasma Metabolites, and Intestinal Microbiota and Metabolites of Weaned Piglets

“…Piglets are vulnerable to physiological, nutritional, and environmental weaning stressors due to the transportation, mixing with other littermates, separation from the sow’s milk, and changes to solid feed and ambient temperature ( Tang et al, 2009 ; Azad et al, 2021 ). These abrupt changes often cause intestinal microbiota imbalance, which has been related to decreased growth rate, changes in gut morphology and microbial populations, and increased susceptibility to scouring and disease ( Reilly et al, 2008 ).…”

Effects of dietary supplementation with chlorogenic acid on growth performance, antioxidant capacity, and hepatic inflammation in broiler chickens subjected to diquat-induced oxidative stress

“…The detrimental consequences of DQ is generally presumed to depend on its capacity to undergo a single electron addition and redox cycling to produce unstable free radicals such as superoxide anion radical, hydrogen peroxide and hydroxyl radical, ultimately leading to devastating effects to cells, including oxidative stress, cellular membrane damage, mitochondrial injury, cellular homeostasis imbalance and inflammation, apoptosis and even death, when the cellular antioxidant protective systems are overwhelmed ( Burk et al, 1995 ; Jones and Vale, 2000 ; Magalhães et al, 2018 ; Azad et al, 2021 ; Jin et al, 2021 ). The liver is responsible for the detoxification of a variety of xenobiotics in vertebrate animals and, therefore, is a major target of DQ ( Magalhães et al, 2018 ).…”

Plant-derived squalene supplementation improves growth performance and alleviates acute oxidative stress-induced growth retardation and intestinal damage in piglets

“…The growth performance of piglets is closely related to their health status, and piglets with oxidative stress usually show inferior growth performance ( Hao et al., 2021 ; Lauridsen, 2019 ). Many studies have shown that diquat-induced oxidative stress causes growth retardation in piglets ( Azad et al., 2021 ; Zheng et al., 2013 ). To further classify whether the antioxidative mechanism is involved in the health-promoting effects of SQ on post-weaning piglets, the piglets were further challenged with diquat to induce acute oxidative stress.…”