Effects of Dietary Modifications on Response of the Duckling to Aflatoxin

Newberne, Paul M.; Wogan, Gerald N.; Hall, Allen

doi:10.1093/jn/90.2.123

Cited by 24 publications

(5 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In groups B and C, the pattern of mortality was similar to the results obtained by Newberne et al [19]. The clinical signs in these groups were related to the report of Gavin [7] in poults and ducklings which included: loss of appetite, nervous symptoms and in young birds, high and rapid mortality.…”

Section: Discussionsupporting

confidence: 86%

“…Even though chemical analysis and immunoassay methods are more sensitive in detection of mycotoxins-(aflatoxin B 1 at 3 ppb) in feed and even in liver, they are not sufficient proofs [7]. Bioassay and demonstration of characteristic biological alterations as clinical signs and pathologic changes by means of animal inoculation strengthen the confirmatory diagnosis of aflatoxicosis in animal [7] [19].…”

Section: Discussionmentioning

confidence: 99%

“…This was carried out following the procedure described by Newberne et al (1966). Thirty six day old ducklings acquired from a local hatchery (at Ibagwa, Enugu State, Nigeria) were randomly divided into six groups (A, B, C, D, E and F) of 6 ducklings each.…”

Section: Bioassay Procedures For Aflatoxin Detectionmentioning

confidence: 99%

See 2 more Smart Citations

Bioassay Procedure for the Diagnosis of Aflatoxicosis in a Pig Farm in Nsukka, South East Nigeria

Shoyinka¹,

Chah²,

Eze³

et al. 2014

OJVM

View full text Add to dashboard Cite

The owner of an intensively reared pig farm in Nsukka, SouthEast Nigeria reported the deaths (within one week) of 90 piglets (2-3 months of age) out of 150 piglets on the farm. The piglets were being fed home-compounded ration composed of spent grain (which appeared moldy) and other locally sourced materials. Clinical signs observed in affected piglets include sudden loss of appetite, diarrhea and distress grunting sound prior to death. Symptomatic treatment of the piglets which included the use of antibiotics (tetracycline, LA) did not appear to have ameliorated the condition. At necropsy carcasses were generally in fair to good body condition; with subcutaneous hemorrhages, mainly under the skin of head and neck regions. Lungs were congested and edematous, with froth along the tracheal and bronchial airways. The liver and spleen were moderately congested, while the mucosae of the gastrointestinal tract (which was free of ingesta) appeared mildly hyperaemic. No pathogenic bacterium was isolated from the heart blood and spleen. Histologic section of the liver showed centrilobular hepatocytes vacoulation and necrosis with hypertrophy of Kupffer cells that were in erythrophagocytosis. There was moderate fibrinous exudation into the interlobular septae. Spleen section showed severe erythrophagocytosis, but mild haemosiderosis. White pulp was either reactive or depopulated. Lungs were severely haemorrhagic with bronchitis and bronchiolitis. A tentative diagnosis of mycotoxicosis was made and the spent grain-compounded ration was fed to different groups of ducklings, with/without arginine and lysine supplementation. On the bases of clinical signs and mortality pattern; gross and histologic changes in the liver of the ducklings, a definitive diagnosis of aflatoxicosis was made. This paper emphasizes the experimental feeding of suspected feeds/feed ingredient to ducklings as a reliable diagnostic model for aflatoxicosis.

show abstract

Section: Discussionsupporting

confidence: 86%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Bioassay Procedure for the Diagnosis of Aflatoxicosis in a Pig Farm in Nsukka, South East Nigeria

Shoyinka¹,

Chah²,

Eze³

et al. 2014

OJVM

View full text Add to dashboard Cite

show abstract

“…The level of AFB 1 was significantly decreased during the autoclaving process at pH 7.4, 9.0, and 11.1, compared with the non-autoclaved samples (p < 0.05). Newberne, Wogan, and Hall (1966) reported that the AFs in contaminated peanut meal were destroyed or eliminated during the autoclaving process. For the soybean based foods such as soy sauce, soy milk, and soybean paste, cooking (usually boiling at 100°C) is one of process in food recipes.…”

Section: Effect Of Autoclaving With Various Ph Treatments On the Redumentioning

confidence: 99%

Reduction of aflatoxins (B1, B2, G1, and G2) in soybean-based model systems

2015

View full text Add to dashboard Cite

“…Aflatoxins are toxic and hepatocarcinogenic agents (5), produced by most of the strains of the Aspergillus parasiticus (Speare) and some of the A. flavus (Link) fungi (6). Although infection of corn by A. flavus has been reported since 1920, corn contamination with aflatoxins was considered a storage problem until 1970 (7).…”

Section: Introductionmentioning

confidence: 99%

Revising the Role of pH and Thermal Treatments in Aflatoxin Content Reduction During the Tortilla and Deep Frying Processes

Torres

Guzman-Ortiz

Ramírez‐Wong

2001

J. Agric. Food Chem.

View full text Add to dashboard Cite

Naturally aflatoxin-contaminated corn (Zea mays L.) was made into tortillas, tortilla chips, and corn chips by the traditional and commercial alkaline cooking processes. The traditional nixtamalization (alkaline-cooking) process involved cooking and steeping the corn, whereas the commercial nixtamalization process only steeps the corn in a hot alkaline solution (initially boiling). A pilot plant that includes the cooker, stone grinder, celorio cutter, and oven was used for the experiments. The traditional process eliminated 51.7, 84.5, and 78.8% of the aflatoxins content in tortilla, tortilla chips, and corn chips, respectively. The commercial process was less effective: it removed 29.5, 71.2, and 71.2 of the aflatoxin in the same products. Intermediate and final products did not reach a high enough pH to allow permanent aflatoxin reduction during thermal processing. The cooking or steeping liquor (nejayote) is the only component of the system with a sufficiently high pH (10.2-10.7) to allow modification and detoxification of aflatoxins present in the corn grain. The importance of removal of tip, pericarp, and germ during nixtamalization for aflatoxin reduction in tortilla is evident.

show abstract

Effects of Dietary Modifications on Response of the Duckling to Aflatoxin

Cited by 24 publications

References 6 publications

Bioassay Procedure for the Diagnosis of Aflatoxicosis in a Pig Farm in Nsukka, South East Nigeria

Bioassay Procedure for the Diagnosis of Aflatoxicosis in a Pig Farm in Nsukka, South East Nigeria

Reduction of aflatoxins (B1, B2, G1, and G2) in soybean-based model systems

Revising the Role of pH and Thermal Treatments in Aflatoxin Content Reduction During the Tortilla and Deep Frying Processes

Contact Info

Product

Resources

About