Effects of Dietary Supplementation with Red Yeast (Sporidiobolus pararoseus) on Productive Performance, Egg Quality, and Duodenal Cell Proliferation of Laying Hens

Abstract

Nowadays, industrial poultry producers are more focused on the safety of their products, especially contaminants from feedstuffs such as mycotoxin and pesticides. The residue from animal production using antibiotic growth promoters (AGPs) may cause some problems with antimicrobial resistance in human and animals. Red yeast (Sporidiobolus pararoseus) has a cell wall consisting of β-glucan and mannan-oligosaccharides and pigments from carotenoids that may be suitable for use as a substitute for AGPs. The objective was to evaluate the effects of red yeast in laying hen diets on productive performance, egg quality, and duodenal health. A total of 22-week-old laying hens (n = 480) were divided into five groups: control diet (CON), AGP at 4.5 g/kg and red yeast supplementation at 1.0 (RY1.0), 2.0 (RY2.0) and 4.0 g/kg (RY4.0) of diet. The results show that the AGP, RY2.0, and RY4.0 groups had significantly higher final body weight compared with the other groups (p < 0.001). The red yeast supplementation improved the egg shape index (p = 0.025), Haugh unit (p < 0.001), and yolk color (p = 0.037), and decreased yolk cholesterol (p < 0.001). Diet with red yeast supplementation improved villus height to crypt depth ratio and crypt cell proliferations. In conclusion, red yeast supplementation at 2.0 g/kg of diet can substitute AGP in layer diet.

Genetic assessment of the effect of red yeast (Sporidiobolus pararoseus) as a feed additive on mycotoxin toxicity in laying hens

“…These observations suggest that red yeast reduced the adsorption of mycotoxins by the liver in hens fed with MT + RY and the applied mycotoxins could not increase lipid peroxidation due to the adsorbent properties of red yeast during the application period. The red yeast cell wall acts as a biological agent that binds to mycotoxin upon intake of the contaminated feed in the gastrointestinal tract to eliminate its toxic effect on vital organs ( Kanmanee et al, 2022 ; Srinual et al, 2022 ). In addition to the adsorption and antioxidant properties of red yeast, several studies in chicken have verified its beneficial effects in improving animal health and productivity, acting as a prebiotic with high nutritional value ( Tapingkae et al, 2018 ; Kanmanee et al, 2022 ; Srinual et al, 2022 ).…”

“…The red yeast cell wall acts as a biological agent that binds to mycotoxin upon intake of the contaminated feed in the gastrointestinal tract to eliminate its toxic effect on vital organs ( Kanmanee et al, 2022 ; Srinual et al, 2022 ). In addition to the adsorption and antioxidant properties of red yeast, several studies in chicken have verified its beneficial effects in improving animal health and productivity, acting as a prebiotic with high nutritional value ( Tapingkae et al, 2018 ; Kanmanee et al, 2022 ; Srinual et al, 2022 ). However, to the best of our knowledge, there are no studies on the effects of red yeast in interaction with multiple mycotoxins supplementation in the chicken diet at molecular and cellular levels in the liver of laying hens.…”

“…The control diet used as the basal diet in this study consisted of a mixture of different cereal grains and oilseed meals (commercial diet). The ingredients and nutrient values of the control diet were given by Kanmanee et al (2022) . In the feeding trial of this study, red yeast (1.0 g/kg) was added to the control diet as a feed supplement and a liquid medium of mixed mycotoxin solutions (100 μg/kg) was sprayed on the control diet as a feed contaminant ( Srinual et al, 2022 ).…”

“…Among biological control agents, yeast is of particular interest and a promising detoxification strategy for the poultry feed industry, being able to significantly degrade mycotoxins by adsorption through the cell wall ( Agriopoulou et al, 2020 ). Red yeast ( Sporidiobolus pararoseus ), a novel yeast used as a mycotoxin binder, acts as a prebiotic with antioxidant properties and possess high nutritional value for improving production traits in poultry species ( Tapingkae et al, 2018 ; Kanmanee et al, 2022 ; Srinual et al, 2022 ).…”

Can Red Yeast (Sporidiobolus pararoseus) Be Used as a Novel Feed Additive for Mycotoxin Binders in Broiler Chickens?

“…The biological damage that is caused by oxidative stress which is caused by free radicals is harmful at the cellular level, and it has been linked to health issues that affect animal productivity [ 32 , 33 ]. In addition to their high nutritional value, the cell wall’s component of red yeast can function as mycotoxin binders [ 28 , 34 ] and improve the productive performance of chickens [ 26 , 35 , 36 ]. Tapingkae et al [ 37 ] demonstrated that the new strain of red yeast that is capable of binding ZEA, AFB1, OTA, and trichothecenes has been commercially used to adsorb mycotoxin in animal and poultry diets.…”