Effects of Different Resistance Training Intensity on Indices of Oxidative Stress

Abstract

The purposes of this study were (a) to determine whether acute resistance exercise training (RET) induces oxidative stress, (b) to determine whether chronic RET decreases oxidative stress level at rest condition in previously untrained men, and (c) also to investigate how the RET intensity influences the training-induced oxidative stress response. Sixteen young men who did not have RET experience in the past were randomly divided in 2 groups. Hypertrophy-intensity group (n = 9) performed 3 sets of 12 repetitions at an intensity corresponding to 70% of 1 repetition maximum (1RM), whereas strength-intensity group (n = 7) performed 3 sets of 6 repetitions at an intensity corresponding to 85% of 1RM. Resistance exercise training involved 6 exercises, and it was performed 3 times a week on nonconsecutive days for 6 weeks. Blood samples were obtained just before (pre-RET) and immediately after RET (post-RET) on the first day of the first week, on the last day of the fourth and sixth weeks. The results indicated that malondialdehyde (MDA) significantly decreased (p < 0.05) in both groups immediately after RET; however, there was no significant acute alteration in glutathione (GSH) level in both groups (p > 0.05). After 6 weeks of training, pre-RET values of MDA significantly decreased and pre-RET values of GSH significantly increased in both hypertrophy- and strength-intensity groups (p < 0.05). These alterations occurred independently of training intensity. This study indicated that hypertrophy- and strength-intensity whole-body RET performed regularly for 6 weeks, decreased MDA concentration and increased GSH level in healthy young men. Results suggest that chronic RET has protective effects against oxidative stress similar to aerobic exercises and that these effects seem to be independent of the training intensity.

Prepubertal children with suitable fitness and physical activity present reduced risk of oxidative stress

“…In a recent study, after 6 weeks of resistance exercise training in young males, GSH levels increased when measured at rest, independent of the training intensity [15]. In light of the results obtained, we may suggest that after-school exercise programs have lower intensity and are healthier, as they limit the OS production.…”

“…Generally, at rest, the ADS is effective at controlling circulating free radicals, limiting cellular damage [14]. However, it has been reported that acute aerobic exercise induces OS, whereas regular aerobic exercise decreases oxidant markers and increases antioxidant enzyme activities [15]. Nonetheless, a substantial debate still exists on this matter, mainly because of controversial findings; in fact, most studies undertaken analyzed the OS profile in professional athletes or sports players habituated to high-intensity agonistic competitions [16][17][18][19], but not in regular practice of exercise or in the general population.…”

Delayed Onset Muscle Soreness and Mechanisms: Relation with Oxidative Stress: Review

“…41 Egzersiz sırasında SR üretimi egzersizin tü-rüne, şiddetine ve süresine bağlıdır. [44][45][46] Bunun en önemli sebebi, farklı egzersiz türlerinin farklı enerji gereksinimlerinin olması ve bundan dolayı farklı oksijen tüketim seviyelerine neden olmasıdır. Bunun sonucunda dokularda oluşturdukları farklı mekanik streslerin etkisi ile farklı kaynaklardan SR üretimini tetiklemesidir.…”

Influência do exercício físico na cognição: uma atualização sobre mecanismos fisiológicos

“…Por fim, cabe ressaltar que o treinamento físico regular de intensidade moderada exerce ação antioxidante 57,58 . Embora os marcadores de estresse oxidativo normalmente avaliados sejam plasmáticos ou séricos, é possível especular que essa ação antioxidante do exercício seja sistêmica e, como tal, atinja também o sistema nervoso central.…”