Introduction: In order to correctly treat hypertension, it is plausible to hypothesize that in the face of regular exercise, these patients would not need anti-hypertensive drugs. Objective: To evaluate the effect of treatment exclusive with exercise on blood pressure (BP) and quality of life (QOL) of hypertensive subjects. Methods: Clinical trial of 32 sedentary hypertensive subjects, 55 ± 9 years, who were under pharmacological treatment (PT) randomly allocated to Exercise Group (EG) and Control Group (CG). At EG, 18 subjects (50% women) at least 10 days after the cessation of PT started the exercise program of 10 weeks, 3x/week, 30 minutes of aerobic exercise followed by resistance exercises, while 14 CG (57% women) remained under PT. Systolic (SBP) and diastolic blood pressure (DBP) was evaluated by auscultation at the beginning and end and QOL were evaluated using the MINICHAL questionnaire.