Effects of Direct Oral Anticoagulants on Quality of Life During Periprocedural Management for Dental Extractions

Cabbar, Fatih; Cabbar, Ayça Türer; Coşansu, Kahraman; Çekirdekçi, Elif İjlal

doi:10.1016/j.joms.2018.11.032

Cited by 6 publications

(11 citation statements)

References 30 publications

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“…With respect to the DASS scale, since only two studies were included, 48,50 we did not perform meta-analysis. Individual data reported in these studies showed a statistically significant decrease favoring NOAC in all the DASS scale domains (total, limitations, burdens, and psychological impact).…”

Section: Dass Scalementioning

confidence: 99%

Satisfaction of Patients with Nonvitamin K Anticoagulants Compared to Vitamin K Antagonists: a Systematic Review and Meta-analysis

et al. 2020

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Objective To undertake a systematic review and meta-analysis to assess the satisfaction of patients receiving nonvitamin K anticoagulants (NOACs), compared with vitamin K antagonists (VKAs). Methods We searched CENTRAL, MEDLINE, Embase, and Clinicaltrials.gov for randomized controlled trials (RCTs) and observational studies. Two reviewers screened, extracted, and appraised data independently. We pooled data using a random-effects model. Outcome included treatment satisfaction, which was assessed by scores of Duke Anticoagulation Satisfaction Scale (DASS), Anticlot Treatment Scale (ACTS), Perception of Anticoagulant Treatment Questionnaire 2 (PACT-Q2), or Treatment Satisfaction Questionnaire for Medication version II (TSQM-VII) and their domains reported with 95% confidence intervals (95% CIs). We followed MOOSE and PRISMA guidelines. Results We included four RCTs and 16 observational studies, enrolling 18,684 participants overall. Compared with VKAs, treatment with NOACs improved the ACTS Burdens score by 4.21 points (95% CI: 2.99–5.43, I 2 = 95%, combined n = 6,180), and ACTS Benefits by 0.49 points (95% CI: 0.18–0.81, I 2 = 85%, combined n = 6,171). Switching from VKAs to NOACs improved the ACTS Burdens score by 5.33 points (95% CI: 3.53–7.14, combined n = 3,097). Compared with VKAs, treatment with NOACs improved the TSQM-VII Global Satisfaction score by 6.86 points (95% CI: 3.00–10.73, combined n = 5,535). Conclusion In patients with nonvalvular atrial fibrillation or venous thromboembolism, NOAC treatment is associated with greater satisfaction compared with VKAs. The switch from VKAs to NOACs was associated with improved patients' satisfaction. These effects were largely due to a lower degree of treatment burden with NOAC treatment.

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Section: Dass Scalementioning

confidence: 99%

Satisfaction of Patients with Nonvitamin K Anticoagulants Compared to Vitamin K Antagonists: a Systematic Review and Meta-analysis

et al. 2020

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“…Nevertheless, this method is not standardized, and no protocol has been developed, as opposed to the available protocol for classic anticoagulants. Another study that compared managing patients under dabigatran, rivaroxaban and apixaban or warfarin is the one performed in 205 patients by Cabbar et al [17]. However, they used an alternative method: they interrupted the pharmacological therapy or gave a bridging therapy upon dental extraction.…”

Section: Discussionmentioning

confidence: 99%

Bleeding Complications in Anticoagulated and/or Antiplatelet-Treated Patients at the Dental Office: A Retrospective Study

Martínez-Moreno

Martínez-López

Rodríguez‐Lozano

et al. 2021

IJERPH

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Background: Bleeding complications in patients undergoing antiplatelet and/or anticoagulant therapy have been one of the main concerns in dental practice. Upon the introduction of new antiplatelet and anticoagulant drugs, there is a search for new protocols that respond to a secure treatment. The aim of the present study was to evaluate bleeding complications in anticoagulated and antiplatelet-treated patients after performing simple dental extractions, in a period of 4 years. Material and Methods: 147 clinical records of anticoagulated and/or antiplatelet-treated patients undergoing a simple dental extraction over a period of 4 years (October 2015 to September 2019) were studied. Within the sample, 63 patients were antiplatelet-treated, 83 were anticoagulated, and 1 patient was under both therapies. Within the anticoagulated patients, 70 took classic anticoagulants and 14 new oral anticoagulants (NOACs). Quantitative data were studied with arithmetic mean and standard deviation (SD). The chi-square test was used for the qualitative variables. ANOVA tests were used to compare age and anticoagulated or antiplatelet-treated patients. Statistical significance was determined when p < 0.05. Results: From the 418 dental extractions performed, five severe bleeding complications took place in three patients (2.11%). From the five events, four were in patients treated with NOACs (1.68%) and one occurred in a patient anticoagulated with acenocoumarol (0.42%; p = 0.003). Conclusions: Considering the results of this retrospective clinical study, we can conclude that bleeding complications in anticoagulated and/or antiplatelet-treated patients after tooth extractions were low, with a higher incidence recorded in patients treated with NOACs, followed by classic anticoagulants, and there were no complications in antiplatelet-treated patients.

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“…2,26 Cabbar et al (2019) investigaron la necesidad del puente de heparina y sugirieron que causaba más hemorragia pero evitaba el riesgo de tromboembolismo. 27 Mientras que, otros estudios en donde se compararon los diferentes protocolos, dio como resultado que no hay diferencias significativas en el sangrado posoperatorio. 28 3.1.3 Reducir (sin suspender) la terapia con antagonistas de la vitamina K Ahmed et al (2019) comentaron que el protocolo de reducir la dosis antes de las extracciones dentales vuelve a producir que el paciente sea susceptible al riesgo de tromboembolismo, por lo que realizarlo tendrá un compromiso más alto.…”

Section: Suspender Los Antagonistas De La Vitamina K Y Administrar Un Puente De Heparina Antes Del Tratamiento Dentalunclassified

“…48 Sin embargo, se debe tomar en cuenta el tipo de medicamento que consume, se ha observado que el riesgo tromboembólico asociado a la suspensión del fármaco es menor en los ACDO en relación con los AVK. 27 En esta revisión hemos recopilado los protocolos más utilizados para el manejo quirúrgico de pacientes anticoagulados.…”

Section: Protocolo Para Extracción En Pacientes Anticoaguladosunclassified

Manejo De La Extracción Dental en Pacientes Sometidos a Terapia Anticoagulante: Una Revisión De La Literatura

Vire

2021

Odontol. Act.

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En los últimos años la extracción de piezas dentales en pacientes que consumen anticoagulantes ha aumentado, y con ello también la necesidad de nuevos estudios que nos permitan conocer cómo abordar dichos casos. La terapia anticoagulante oral se utiliza para prevenir enfermedades de tipo tromboembólico. Entre los anticoagulantes tenemos los Antagonistas de la vitamina K y los Anticoagulantes directos orales. El objetivo de este estudio es analizar el tipo de manejo que necesita un paciente anticoagulado, además de las limitaciones, indicaciones y medidas hemostáticas para la extracción dental en estos pacientes. Se realizó una búsqueda en las bases digitales de Pubmed, Science Direct, Cochrane y SciELO, obteniendo un total de 2176 artículos que luego de la implementación de criterios de inclusión y exclusión dio como resultado 59 artículos para esta revisión bibliográfica. El manejo en estos pacientes debe realizarse con suma cautela tomando en cuenta su estado sistémico, se realizará la extracción de manera segura sin suspensión ni modificación del medicamento, cuando se ha planificado la intervención quirúrgica con una técnica atraumática de una a tres piezas y el INR es ≤3.5. Es fundamental para el odontólogo tener el conocimiento actualizado del trato a pacientes anticoagulados y sus complicaciones hemorrágicas.

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Effects of Direct Oral Anticoagulants on Quality of Life During Periprocedural Management for Dental Extractions

Cited by 6 publications

References 30 publications

Satisfaction of Patients with Nonvitamin K Anticoagulants Compared to Vitamin K Antagonists: a Systematic Review and Meta-analysis

Satisfaction of Patients with Nonvitamin K Anticoagulants Compared to Vitamin K Antagonists: a Systematic Review and Meta-analysis

Bleeding Complications in Anticoagulated and/or Antiplatelet-Treated Patients at the Dental Office: A Retrospective Study

Manejo De La Extracción Dental en Pacientes Sometidos a Terapia Anticoagulante: Una Revisión De La Literatura

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