2016
DOI: 10.1007/s12018-016-9220-6
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Effects of Drugs on Bone Quality

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Cited by 8 publications
(4 citation statements)
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“…On the other hand, Mellibovsky et al indicated that teriparatide improved the properties of the material in patients with glucocorticoid-induced osteoporosis 11 . In this study we found a small but significant effect of PTH on tissue hardness, probably related to PTH-induced changes in bone remodeling 17,18 . H mean : average; SD: standard deviation; Sup: superior; Inf: inferior; SR: stroncio ranelate.…”
Section: Originalsmentioning
confidence: 48%
“…On the other hand, Mellibovsky et al indicated that teriparatide improved the properties of the material in patients with glucocorticoid-induced osteoporosis 11 . In this study we found a small but significant effect of PTH on tissue hardness, probably related to PTH-induced changes in bone remodeling 17,18 . H mean : average; SD: standard deviation; Sup: superior; Inf: inferior; SR: stroncio ranelate.…”
Section: Originalsmentioning
confidence: 48%
“…However, it is important to remember that skeletal indicators considered for the reconstruction of the biological profile are influenced by a number of factors including age, sex, disease, genetics, lifestyle, diet, and pertinent here, possibly the use of prescription drugs (medical and non-medical) and other commonly used drugs, such as those drugs of abuse. Indeed, the medical literature describes how various drugs can affect the skeleton [14] and thus modify characteristic bone quality, appearance, shape and size of skeletal areas [15], which are used for the reconstruction of the biological profile.…”
Section: Introductionmentioning
confidence: 99%
“…The cellular mechanisms of action of GIOP include disruption of the Wnt /LRP5 signalling pathway, leading to reduction of new bone formation, via osteoblastic suppression and increased osteoblast apoptosis [12] , [22] . Further, GC action prolongs osteoclast lifespan, which leads to greater bone resorption [11] .…”
Section: Introductionmentioning
confidence: 99%