Effects of Early Versus Delayed Excision and Grafting on Restoring the Functionality of Deep Burn-Injured Hands: A Double-Blind, Randomized Parallel Clinical Trial

Ayaz, Mehdi; Karami, Mohammad Reza; Deilami, Iman; Moradzadeh, Zahra

doi:10.1093/jbcr/irz033

Cited by 13 publications

(7 citation statements)

References 24 publications

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“…Deep burn often requires multiple debridement and skin grafting to repair the wound, and scar hyperplasia and contracture often accompany the wound healing, which seriously affects the patient's quality of life. At present, the main method to solve the dysfunction caused by scar contracture is skin graft after scar resection, while patients with deep burns are often faced with the problem of severe shortage of their own skin sources [ 7 , 8 ]. In recent years, with the development of tissue engineering, medical collagen sponge has been widely used in the field of wound repair.…”

Section: Introductionmentioning

confidence: 99%

Analysis of the Curative Effect and Influencing Factors of Collagen Sponge Combined with Autologous Skin Graft in the Treatment of Deep Burn Patients

Cai

Jiang

Zang

2021

Evidence-Based Complementary and Alternative Medicine

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Burn is one of the common traumatic diseases in clinics. After deep burn, the complicated changes of the condition are caused by the burn wound, which ends with the repair of the wound. For patients with deep burns, whether the wound can be repaired as soon as possible is the key to the success of clinical treatment. For patients with deep burns, due to the lack of an autologous skin source, scar hyperplasia at donor site, skin graft repair at donor site, postoperative flap necrosis, and other problems in traditional surgical procedures, the method of improving function only by an autologous skin source has been unable to perform the later function reconstruction in patients with deep burns. In this study, collagen sponge combined with autologous skin graft was used to treat patients with deep burn, and the clinical efficacy of the patients was observed, and the related factors affecting the efficacy of the patients were analyzed. The results showed that collagen sponge combined with autologous skin graft was effective in the treatment of deep burn patients, and it was worth popularizing. Deep III-IV degree burns, wound infection, and hospital stay >3 months are all risk factors affecting the postoperative curative effect of patients. Therefore, in the clinical work, we should focus on patients with deep III-IV degree burns, perform surgery as soon as possible, and actively deal with wounds to prevent infection, which is beneficial to improve the curative effect.

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Section: Introductionmentioning

confidence: 99%

Analysis of the Curative Effect and Influencing Factors of Collagen Sponge Combined with Autologous Skin Graft in the Treatment of Deep Burn Patients

Cai

Jiang

Zang

2021

Evidence-Based Complementary and Alternative Medicine

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“…Minimum clinically important changes for scoring system in the JTT and MHQ have not been established in patients with burns. However, results of the JJT and MHQ showed significantly the improvements in VR group [16,21]. Participants were able to engage with the VR system and complete the interventions without premature withdrawal or non-adherence.…”

Section: Discussionmentioning

confidence: 89%

Effects of Virtual Reality-Based Rehabilitation on Burned Hands: A Prospective, Randomized, Single-Blind Study

Joo

Cho

Lee

et al. 2020

JCM

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Hands are the most frequent burn injury sites. Appropriate rehabilitation is essential to ensure good functional recovery. Virtual reality (VR)-based rehabilitation has proven to be beneficial for the functional recovery of the upper extremities. We investigated and compared VR-based rehabilitation with conventional rehabilitation (CON) in patients with burned hands. Fifty-seven patients were randomized into a VR or CON group. Each intervention was applied to the affected hand for four weeks, and clinical and functional variables were evaluated. Hand function was evaluated before intervention and four weeks after intervention using the Jebsen-Taylor hand function test (JTT), Grasp and Pinch Power Test, Purdue Pegboard test (PPT), and Michigan Hand Outcomes Questionnaire (MHQ). The JTT scores for picking up small objects and the MHQ scores for hand function, functional ADL, work, pain, aesthetics, and patient satisfaction were significantly higher in the VR group than in the CON group (p < 0.05). The results suggested that VR-based rehabilitation is likely to be as effective as conventional rehabilitation for recovering function in a burned hand. VR-based rehabilitation may be considered as a treatment option for patients with burned hands.

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“…69–71 The timing of reconstructive surgery had mixed results in terms of affecting the rate of burn contracture. 72–75…”

Section: Resultsmentioning

confidence: 99%

“…[69][70][71] The timing of reconstructive surgery had mixed results in terms of affecting the rate of burn contracture. [72][73][74][75] Lasers were utilized in 17 studies with overall good results. (See table, Supplemental Digital Content 10, which displays a table summarizing articles which discussed preventative and reconstructive options using laser therapy for burn contractures, http://links.lww.…”

Section: Overview Of Techniquesmentioning

confidence: 99%

Prevention and Treatment of Burn Scar Contracture: A Practical Review

Raborn,

Janis

2024

Plastic and Reconstructive Surgery - Global Open

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Summary: Burn contracture affects close to one-third of all burn patients, leading to significant functional impairment and costs. Effective prevention and treatment strategies are necessary to decrease morbidity and unnecessary costs. This scoping review aimed to summarize prevention and treatment strategies used for management of burn scar contractures published in the literature since 2000. A comprehensive PubMed review was performed in October 2022 to identify methods of burn contracture prevention and treatments. Non-English, duplicate, and unavailable articles were excluded. Data were extracted including publication year, techniques, and outcomes. A total of 327 publications met criteria for inclusion. Most articles were published in 2011 (n = 22). Treatment strategies were discussed in 82.9% of studies, prevention in 16.5%, and both in 0.6%. The most common areas discussed included the upper extremity (n = 127) and neck (n = 102). Flaps were the most frequently used method (n = 208), followed by autografts (n = 89). Most preventative therapies were still in early stages of development. Burn contracture management requires a highly individualized approach with many available reconstructive techniques available. Further research is needed to improve prevention techniques and decrease morbidity and cost to patients.

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Effects of Early Versus Delayed Excision and Grafting on Restoring the Functionality of Deep Burn-Injured Hands: A Double-Blind, Randomized Parallel Clinical Trial

Cited by 13 publications

References 24 publications

Analysis of the Curative Effect and Influencing Factors of Collagen Sponge Combined with Autologous Skin Graft in the Treatment of Deep Burn Patients

Analysis of the Curative Effect and Influencing Factors of Collagen Sponge Combined with Autologous Skin Graft in the Treatment of Deep Burn Patients

Effects of Virtual Reality-Based Rehabilitation on Burned Hands: A Prospective, Randomized, Single-Blind Study

Prevention and Treatment of Burn Scar Contracture: A Practical Review

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