Effects of eCG and FSH in timed artificial insemination treatment regimens on estrous expression and pregnancy rates in primiparous and multiparous Bos indicus cows

Bottino, M. P.; Simões, L. M. S.; Silva, L.A.C.L.; Girotto, R. W.; Scandiuzzi, L.A.; Massoneto, J.P.M.; Baruselli, Pietro Sampaio; Souza, José Camisão de; Sales, J. N. S.

doi:10.1016/j.anireprosci.2021.106751

Cited by 6 publications

(5 citation statements)

References 32 publications

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“…However, this effect is more evident in beef cows with more pronounced anestrous condition (Baruselli et al, 2004). The application of eCG can be used to improve the conception rates of cows in postpartum anestrus or cows without CL at the beginning of the FTAI protocol, especially in primiparous cows (Sales et al, 2016;Bottino et al, 2021).…”

Section: Resultsmentioning

confidence: 99%

Strategic re-use of intravaginal progesterone devices increases conception rate in primiparous Nellore cows

Jesus

Neri

Lima

et al. 2023

Semina: Ciênc. Agrár.

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In the present study, we investigate the effect of the presence or absence of corpus luteum (CL) at the beginning of a fixed-time artificial insemination (FTAI) protocol and to evaluate the impact of one-time use of intravaginal progesterone device (P4 device) in cows with or without CL. A total of 776 primiparous Nellore cows were subjected to FTAI approximately 45 days postpartum. In Experiment 1, 476 cows were divided into two experimental groups: with (CL-present, n=113) or without (CL-absent, n=363) CL, after ultrasound evaluation. On day 0 (D0), all cows received a new P4 device (1.0 g) and 2.0 mg estradiol benzoate (EB). Eight days later (D8), the P4 devices were withdrawn, and prostaglandin (15 mg), estradiol cypionate (0.5 mg), and eCG (300 IU) were administered i.m. All cows were inseminated 48 h after P4 device withdrawal (D10). In Experiment 2, the cows (n= 300) received (at D0) P4 devices that were previously used once in other cows with (n=109) or without CL (n=191) and 2 mg of EB. The same protocol as that used in Experiment 1 was performed from D8 onwards. In Experiment 1, the overall conception rate after FTAI was 55% (262/476). No difference was found in the conception rate between CL-present and CL-absent cows (52.2 vs. 55.5%). In Experiment 2, the conception rate obtained with P4 devices previously used in cows with CL (58.7%) was greater (P<0.05) than that obtained with P4 devices previously used in cows without CL (42.9%). Thus, this strategy resulted in a 15.8% increase in conception rate. In conclusion, the presence or absence of CL at the beginning of the FTAI protocol did not affect the conception rate in cows synchronized with the new P4 device, but the insertion of P4 devices previously used in cows with CL enhanced the conception rates in cows without CL.

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Section: Resultsmentioning

confidence: 99%

Strategic re-use of intravaginal progesterone devices increases conception rate in primiparous Nellore cows

Jesus

Neri

Lima

et al. 2023

Semina: Ciênc. Agrár.

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“…The decrease may be due to the increased quality of oocyte ovulated from a better follicle blood flow in the eCG treated groups, since follicular fluid is mainly derived from blood plasma and its content influences oocyte quality (Kumar et al, 2015(Kumar et al, , 2014. Also, eCG effect in the final maturation of follicles, longer half-life (when compared to other gonadotropins) and stimulation for estradiol production (Bottino et al, 2021;Bukar et al, 2012;Hosseini et al, 2018;Riesenberg et al, 2001) may also be considered relevant factors for the better results found by Andrade et al (2021) for eCG treated group.…”

Section: Discussionmentioning

confidence: 99%

Influence of eCG and reproductive management in the resynchronization of ovulation in dairy goats

et al. 2022

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Resynchronization protocols have been proposed as a way of shortening females' unproductive time in the flock, with good results in cattle and sheep. In goats, initial studies have shown that a second progestogen device inserted before luteolysis and pregnancy diagnosis does not interfere with the corpus luteum lifespan or functionality. This study aimed to evaluate the follicular growth, ovulation pattern and pregnancy rate after insertion of a second and new progestogen device for resynchronizing, with or without equine Chorionic Gonadotrophin (eCG), submitted to natural mating (NM) or artificial insemination (AI) to propose a viable resynchronization protocol for dairy goats. A total of 38 multiparous Saanen goats underwent a short-term progesterone protocol [six days exposed to medroxyprogesterone acetate (MAP) intravaginal sponges + 200 IU eCG and 0.12 mg of cloprostenol sodium on the 5 th day + 0.025 mg of lecirelin 34 hours after sponge withdrawal] and, on day 16th after the ovulation, received a new MAP device which was retained until day 21. At this moment females were split into four groups: G eCG+NM -100 IU eCG with NM; G Sal+NM -saline solution with NM; G eCG+AI -100 IU eCG with AI; and G Sal+AI -saline solution with AI. Ultrasound scans were performed every 12 h from sponge withdrawal (day 21) until 108 h after sponge withdrawal (day 25) for follicular dynamics evaluation, at 240 h (day 31) for assessing the presence of active corpus luteum, and on day 60 for pregnancy diagnosis. No differences were found regarding ovulation time, synchronization and follicle size. However, G eCG+NM presented a greater estrus manifestation rate (100%) and pregnancy rate (62.5%) when compared to G Sal+AI . In conclusion, resynchronization protocols in dairy goats may present satisfactory results.

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“…Among the available hormone protocols for heifers, the use of follicle stimulating hormone (FSH) and equine chorionic gonadotropin (eCG) are widely used in Brazil [ 16 ]. FSH is a glycoprotein produced and secreted by gonadotrophic cells, which are present in the anterior region of the pituitary gland [ 17 ].…”

Section: Introductionmentioning

confidence: 99%

“…Differently from FSH, equine chorionic gonadotropin (eCG) is naturally produced in the mare’s endometrial calyces during gestation (40 to 130 days). Its use in FTAI programs in cattle can improve fertility rates, especially in heifers and in recent postpartum cows [ 19 ], with a recent study showing a positive effect in pregnancy rates [ 16 ]; however, some studies have not been able to demonstrate the effectiveness of eCG in FTAI protocols for beef heifers [ 20 ]. Equine chorionic gonadotropin can bind to the FSH and luteinizing hormone (LH) receptors, possessing activities directly related to follicular development; therefore, it can provide follicular growth and maturation, and consequently, ovulation [ 21 ].…”

Section: Introductionmentioning

confidence: 99%

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Follicular Dynamics and Pregnancy Rate in Nellore Heifers Submitted to Fixed-Time Artificial Insemination Protocols (FTAI)

Silva

Neves

Correa

et al. 2022

Veterinary Sciences

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This study aimed to evaluate follicular dynamics and pregnancy rates in Nellore heifers submitted to fixed-time artificial insemination (FTAI) protocols associated with equine chorionic gonadotrophin (eCG) or follicle stimulating hormone (FSH). Nellore heifers (n = 259) were used, divided into two studies. Experiment I evaluated the ovarian follicular dynamics in 64 Nellore heifers submitted to different FTAI protocols (n = 32/group) using either FSH or eCG. In Experiment II, the pregnancy rate was evaluated in 195 heifers submitted to FTAI protocols and divided into two groups: FSH (n = 97) and eCG (n = 98). In Experiment I, the ultrasound examination showed that the maximum diameter of the dominant and preovulatory follicles and the ovulation time were similar between the FSH and eCG groups (p > 0.05). However, the ovulation rate was higher in the eCG group when compared to FSH (p = 0.014). In Experiment II, females that received eCG presented a higher pregnancy rate (58.1%) when compared to FSH (40.2%) (p = 0.012). The use of eCG in the FTAI protocol in Nellore heifers promoted a higher ovulation rate and increased pregnancy rate and may be the most suitable alternative to increase conception rates in animals that are raised in an extensive system under tropical conditions in the Amazon.

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Effects of eCG and FSH in timed artificial insemination treatment regimens on estrous expression and pregnancy rates in primiparous and multiparous Bos indicus cows

Cited by 6 publications

References 32 publications

Strategic re-use of intravaginal progesterone devices increases conception rate in primiparous Nellore cows

Strategic re-use of intravaginal progesterone devices increases conception rate in primiparous Nellore cows

Influence of eCG and reproductive management in the resynchronization of ovulation in dairy goats

Follicular Dynamics and Pregnancy Rate in Nellore Heifers Submitted to Fixed-Time Artificial Insemination Protocols (FTAI)

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