Effects of ecosystem stress on reproduction and development

Gallo, Alessandra; Tosti, Elisabetta

doi:10.1002/mrd.23169

Cited by 13 publications

(11 citation statements)

References 34 publications

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“…Anthropogenic human activities and xenobiotics released into the environment such as metals, pesticides, herbicides, drugs, antifouling compounds, nanoparticles, and plastics directly influence migration, seasonal breeding, and reproduction [4][5][6]. These factors also have secondary deleterious effects contributing to climate change, as evidenced in global warming and ocean acidification, raising an alarm in the scientific community and government environmental agencies about reprotoxicity [7,8]. In particular, there is growing evidence on how higher temperatures can act together with even low chemical concentrations of pollutants to elicit significant effects, undermining the traditional risk assessment paradigm for establishing threshold conditions below which a compound is not considered a threat [5,9].…”

Section: Introductionmentioning

confidence: 99%

Antioxidative Defense and Fertility Rate in the Assessment of Reprotoxicity Risk Posed by Global Warming

Parisi

Guerriero

2019

Antioxidants

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The objective of this review is to briefly summarize the recent progress in studies done on the assessment of reprotoxicity risk posed by global warming for the foundation of strategic tool in ecosystem-based adaptation. The selected animal data analysis that was used in this paper focuses on antioxidative markers and fertility rate estimated over the period 2000–2019. We followed a phylogenetic methodology in order to report data on a panel of selected organisms that show dangerous effects. The oxidative damage studies related to temperature fluctuation occurring in biosentinels of different invertebrate and vertebrate classes show a consistently maintained physiological defense. Furthermore, the results from homeothermic and poikilothermic species in our study highlight the influence of temperature rise on reprotoxicity.

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Section: Introductionmentioning

confidence: 99%

Antioxidative Defense and Fertility Rate in the Assessment of Reprotoxicity Risk Posed by Global Warming

Parisi

Guerriero

2019

Antioxidants

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“…Overall, collective findings indicate defects in reproductive function across a wide range of marine and terrestrial animals including fish [70], birds [71], alligators, turtles, salamanders [72], mice [73], and panthers [74], when exposed to CECs. There is considerable evidence that chemical pollution commonly interferes with hormone function, leading to endocrine disruption [75]. Due to the vulnerability of hormone-receptor systems, certain endocrine disruptors affect normal reproductive functions as well as embryo development [75].…”

Section: Impact Of Cecs On Male Fertilitymentioning

confidence: 99%

“…There is considerable evidence that chemical pollution commonly interferes with hormone function, leading to endocrine disruption [75]. Due to the vulnerability of hormone-receptor systems, certain endocrine disruptors affect normal reproductive functions as well as embryo development [75]. Therefore, CECs causing hormone disruption or direct damage to spermatogenesis may be responsible for changes in male reproduction (Figure 2) [13,75].…”

Section: Impact Of Cecs On Male Fertilitymentioning

confidence: 99%

Contaminants of Emerging Concern (CECs) and Male Reproductive Health: Challenging the Future with a Double-Edged Sword

Marcu

Keyser

Petrik

et al. 2023

Toxics

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Approximately 9% of couples are infertile, with half of these cases relating to male factors. While many cases of male infertility are associated with genetic and lifestyle factors, approximately 30% of cases are still idiopathic. Contaminants of emerging concern (CECs) denote substances identified in the environment for the first time or detected at low concentrations during water quality analysis. Since CEC production and use have increased in recent decades, CECs are now ubiquitous in surface and groundwater. CECs are increasingly observed in human tissues, and parallel reports indicate that semen quality is continuously declining, supporting the notion that CECs may play a role in infertility. This narrative review focuses on several CECs (including pesticides and pharmaceuticals) detected in the nearshore marine environment of False Bay, Cape Town, South Africa, and deliberates their potential effects on male fertility and the offspring of exposed parents, as well as the use of spermatozoa in toxicological studies. Collective findings report that chronic in vivo exposure to pesticides, including atrazine, simazine, and chlorpyrifos, is likely to be detrimental to the reproduction of many organisms, as well as to sperm performance in vitro. Similarly, exposure to pharmaceuticals such as diclofenac and naproxen impairs sperm motility both in vivo and in vitro. These contaminants are also likely to play a key role in health and disease in offspring sired by parents exposed to CECs. On the other side of the double-edged sword, we propose that due to its sensitivity to environmental conditions, spermatozoa could be used as a bioindicator in eco- and repro-toxicology studies.

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“…Water, air, and soil pollution, together with climatic changes, have been shown to impact gamete quality, fertilization, and embryo and fetal development [5,173]. Due to this worldwide alarming concern, at present, all governments are initiating the adoption of green revolution interventions to decrease CO 2 levels in the atmosphere aimed at slowing down, or even regressing, this harmful trend.…”

Section: Resilience Of Life Style Impact On Reproductionmentioning

confidence: 99%

Reprotoxic Impact of Environment, Diet, and Behavior

Gallo

2022

IJERPH

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Reproductive health is progressively declining due to multiples endogenous and exogenous factors, such as environmental contaminants, diet and behavior. Accumulated evidences confirm that fertility and reproductive function have been adversely affected by exposure to chemical contaminants released in the environment. Today, the impact of diet and behavior on reproductive processes is also receiving special attention from the scientific community. Indeed, a close relationship between diet and fertility has been proven. Furthermore, a combination of unhealthy behavior, such as exposure to hazardous compounds and stress factors, poses living organisms at higher risk of reprotoxic effects. In particular, it has been described that poor life behaviors are associated with reduced male and female fertility due to decreased gamete quality and function. Most of the erroneous behaviors are, furthermore, a source of oxidative stress that, leading to epigenetic alterations, results in an impaired reproductive fitness. This review reports the detrimental impact of the most common environmental chemical stressors, diet, and behavior on reproductive functionality and success. Although clear evidences are still scarce, reassuring data are provided that a healthy diet and reverting unhealthy lifestyles may be of help to recover physiological reproductive conditions.

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Effects of ecosystem stress on reproduction and development

Cited by 13 publications

References 34 publications

Antioxidative Defense and Fertility Rate in the Assessment of Reprotoxicity Risk Posed by Global Warming

Antioxidative Defense and Fertility Rate in the Assessment of Reprotoxicity Risk Posed by Global Warming

Contaminants of Emerging Concern (CECs) and Male Reproductive Health: Challenging the Future with a Double-Edged Sword

Reprotoxic Impact of Environment, Diet, and Behavior

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